Browsing by Author "Zagorevski, Dmitri V."

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Analysis of E. coli K5 capsular polysaccharide heparosan

Ly, Mellisa; Wang, Zhenyu; Laremore, Tatiana N.; Zhang, Fuming; Zhong, Weihong; Pu, Dennis; Zagorevski, Dmitri V.; Dordick, Jonathan S.; Linhardt, Robert J. (Springer, 2011-01-01)

Heparosan is the key precursor for the preparation of bioengineered heparin, a potential replacement for porcine intestinal heparin, an important anticoagulant drug. The molecular weight (MW) distribution of heparosan ...
High-resolution preparative separation of glycosaminoglycan oligosaccharides by polyacrylamide gel electrophoresis

Laremore, Tatiana N.; Ly, Mellisa; Solakyildirim, Kemal; Zagorevski, Dmitri V.; Linhardt, Robert J. (Elsevier, 2010-01-01)

Separation of milligram amounts of heparin oligosaccharides ranging in degree of polymerization from 4 to 32 is achieved within 6h using continuous elution polyacrylamide gel electrophoresis (CE-PAGE) on commercially ...
Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis of Uncomplexed Highly Sulfated Oligosaccharides using Ionic Liquid Matrices

Laremore, Tatiana N.; Murugesan, Saravanababu; Park, Tae Joon; Avci, Fikri Y.; Zagorevski, Dmitri V.; Linhardt, Robert J. (American Chemical Society (ACS), 2006-03-15)

Direct UV matrix-assisted laser desorption/ionization (MALDI) mass spectrometric analysis of uncomplexed, underivatized, highly sulfated oligosaccharides has been carried out using ionic liquids as matrices. Under ...