Astrobiological exploration of RNA oligomerization and reaction product characterization for prebiotically based chemical reactions
Authors
Burcar, Bradley Thomas
ORCID
Loading...
Other Contributors
McGown, Linda Baine
Rogers, Karyn
Watson, E. Bruce
Whittet, D. C. B. (Doug C. B.)
Ryu, Chang Yeol
Linhardt, Robert J.
Rogers, Karyn
Watson, E. Bruce
Whittet, D. C. B. (Doug C. B.)
Ryu, Chang Yeol
Linhardt, Robert J.
Issue Date
2015-08
Keywords
Chemistry
Degree
PhD
Terms of Use
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
Full Citation
Abstract
The formation of aggregates from circular and linear oligomers from conventional prebiotic reactions using activated nucleotides and montmorillonite clay catalysts are shown and characterized using MALDI-TOF mass spectrometry. These non-covalent aggregates can lead to misclassification of reaction products and may interfere with proper interpretation of results utilizing a number of analytical techniques. This aggregation was also shown to be enhanced under high pressure conditions of 5 and 10 kbar. This aggregation appears to not inhibit the formation of long oligomers for the investigated reactions at 5 kbar, but may play a significant role in inhibiting oligomerization at 10 kbar.
Description
August 2015
School of Science
School of Science
Department
Dept. of Chemistry and Chemical Biology
Publisher
Rensselaer Polytechnic Institute, Troy, NY
Relationships
Rensselaer Theses and Dissertations Online Collection
Access
Restricted to current Rensselaer faculty, staff and students. Access inquiries may be directed to the Rensselaer Libraries.