Molecular dynamics simulations of ssDNA and gmp/G-quadruplex
Authors
Wilbanks, Cecily C.
ORCID
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Other Contributors
McGown, Linda Baine
Garde, Shekhar
Cramer, Steven M.
Dinolfo, Peter
Colón, Wilfredo
Garde, Shekhar
Cramer, Steven M.
Dinolfo, Peter
Colón, Wilfredo
Issue Date
2015-08
Keywords
Chemistry
Degree
PhD
Terms of Use
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
Full Citation
Abstract
Even as more information becomes available using experimental methods, chemistry is evolving into a discipline in which both theoretical and experimental aspects can be used to better understand and interpret chemical processes and mechanisms. Molecular dynamics simulations provide a means by which we may explore atomic interactions within molecules in a straightforward and cost-effective manner. Here we use molecular dynamics to study two separate but related areas of research in the McGown group: self-assembly of guanosine monophosphate (GMP) into G-quadruplex (G4) structures, and the mechanism of separation of same-length, single-stranded DNA based on sequence in capillary zone electrophoresis.
Description
August 2015
School of Science
School of Science
Department
Dept. of Chemistry and Chemical Biology
Publisher
Rensselaer Polytechnic Institute, Troy, NY
Relationships
Rensselaer Theses and Dissertations Online Collection
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