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dc.rights.licenseRestricted to current Rensselaer faculty, staff and students. Access inquiries may be directed to the Rensselaer Libraries.
dc.contributorKoffas, Mattheos A. G.
dc.contributorLinhardt, Robert J.
dc.contributorKane, Ravi S.
dc.contributorMaxwell, Patrick H.
dc.contributor.authorToparlak, Omer Duhan
dc.date.accessioned2021-11-03T08:29:54Z
dc.date.available2021-11-03T08:29:54Z
dc.date.created2015-10-07T15:58:04Z
dc.date.issued2015-08
dc.identifier.urihttps://hdl.handle.net/20.500.13015/1568
dc.descriptionAugust 2015
dc.descriptionSchool of Engineering
dc.description.abstractIn the last decade, metabolic engineering benefited greatly from systems and synthetic biology due to substantial advancements in those fields. As a result, technologies and methods evolved to be more complex and controllable than ever. In this thesis, we aimed to improve existing genome engineering technologies to develop controllable and predictable metabolic pathway optimization tool in Saccharomyces cerevisiae. Moreover, we applied up-to-date metabolic engineering pathway balancing techniques to produce drop-in gasoline-replica hydrocarbon biofuels as long-chain alkanes from biological waste, by targeting pathway enzymes into peroxisomes. Lastly, we aimed to engineer the central carbon metabolism of Saccharomyces cerevisiae to develop an acetyl-CoA overproducing strain from biological waste for the production of variety of high-value chemicals and biofuels originated and derived from acetyl-CoA.
dc.language.isoENG
dc.publisherRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofRensselaer Theses and Dissertations Online Collection
dc.subjectChemical engineering
dc.titleCompartmentalization of metabolic pathways into peroxisomes of Saccharomyces cerevisiae
dc.typeElectronic thesis
dc.typeThesis
dc.digitool.pid176840
dc.digitool.pid176841
dc.digitool.pid176842
dc.rights.holderThis electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
dc.description.degreeMS
dc.relation.departmentDept. of Chemical and Biological Engineering


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