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dc.rights.licenseUsers may download and share copies with attribution in accordance with a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License. No commercial use or derivatives are permitted without the explicit approval of the author.
dc.contributorDe, Suvranu
dc.contributorManiatty, Antoinette M.
dc.contributorZhang, Lucy T.
dc.contributor.authorJin, Congran
dc.date.accessioned2021-11-03T08:34:59Z
dc.date.available2021-11-03T08:34:59Z
dc.date.created2016-06-13T11:09:44Z
dc.date.issued2016-05
dc.identifier.urihttps://hdl.handle.net/20.500.13015/1655
dc.descriptionMay 2016
dc.descriptionSchool of Engineering
dc.description.abstractA multi-physics computational model has been developed to investigate the thermomechanical response of the ultrasonically activated soft tissue. In pursuit of better understanding of the extent of deformation of soft tissues subjected to harmonic excitations, the cellular level cavitational effect has been incorporated in the tissue level continuum model to accurately determine the thermodynamic states such as temperature and pressure. The cavitation model based equation of state (EOS) captures the additional pressure as a result of evaporation of intracellular and cellular water by absorbing heat due to frictional heating in the tissue, and temperature in the continuum level thermomechanical model. The extent of deformation of the soft tissue is studied for the simulated range of frequencies of harmonic oscillations and applied loads. The model is shown to capture characteristics of ultrasonically activated soft tissue deformation and temperature fields. At the cellular level, evaporation of water below 100°C is indicative of protein denaturation and coagulation much below the boiling temperature under ambient conditions. Further, it is revealed that with the increasing operating frequency and loading, the evaporation of water starts earlier, which may lead to accelerated protein denaturation and coagulation.
dc.language.isoENG
dc.publisherRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofRensselaer Theses and Dissertations Online Collection
dc.subjectMechanical engineering
dc.titleModeling of the thermomechanical response of ultrasonically activated soft tissue
dc.typeElectronic thesis
dc.typeThesis
dc.digitool.pid177202
dc.digitool.pid177204
dc.digitool.pid177206
dc.rights.holderThis electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
dc.description.degreeMS
dc.relation.departmentDept. of Mechanical, Aerospace, and Nuclear Engineering


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