In today’s increasingly higher speed and higher data rate world, high speed Analog to Digital Converters (ADCs) are very much in demand. They are needed in multiple applications including communications, radars, software ...

In addition to the study of three different practical designs, generic investigations on the scaling effect and pebble wear are also conducted. The coupled modeling approach developed in this thesis can provide better ...

For the second half of this work, we move to a biological context in which we studied the effect of specific mutations in a protein. We find that in the context of the DnaE intein, mutations to the Thr69 residue can alter ...

In this research, a detailed procedure for effective calibration was introduced by decoupling the different phenomena in the experimental tests during the calibration process. This procedure maximizes the robustness of the ...

SPD.

Here I describe the structure-based design of macromolecular bioconjugates for the effective inhibition of three different diseases with broad public interest: anthrax, influenza, and HIV/AIDS. To that end, I have synthesized ...

Myosin is the molecular motor that powers muscle contraction. Variation between myosin isoforms is a major determinant of muscle mechanical properties including shortening velocity and perhaps stretch activation (SA). We ...