Inteins as biomolecular switches : applications in drug discovery, protein purification, and stress response

Authors
Pearson, C. Seth
ORCID
Thumbnail Image
Files
179005_Pearson_rpi_0185E_11217.pdf (3.36 MB)
Other Contributors
Belfort, Georges
Belfort, Marlene
Karande, Pankaj
Shekhtman, Alexander
Issue Date
2018-05
Keywords
Chemical engineering
Degree
PhD
Terms of Use
This electronic version is a licensed copy owned by Rensselaer Polytechnic Institute, Troy, NY. Copyright of original work retained by author.
Full Citation
URI
https://hdl.handle.net/20.500.13015/2198
Abstract
Inteins are protein elements that autocatalytically excise themselves from a host protein in a process called protein splicing. The two flanking sequences of the host protein, called the N- and C-exteins, are subsequently ligated with a native peptide bond, resulting in a mature protein.
Description
May 2018
School of Engineering
Department
Dept. of Chemical and Biological Engineering
Publisher
Rensselaer Polytechnic Institute, Troy, NY
Relationships
Rensselaer Theses and Dissertations Online Collection
Access
Restricted to current Rensselaer faculty, staff and students. Access inquiries may be directed to the Rensselaer Libraries.
Collections
RPI Theses Online (Complete)