Browsing RPI Theses Online (Complete) by Author "Dai, Guohao"
Now showing items 1-17 of 17
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A combined experimental approach to investigate the underlying mechanisms of history-dependent phenomena in skeletal muscle : the Drosophila jump muscle and single fiber tissue engineering
Koppes, Ryan Alan (Rensselaer Polytechnic Institute, Troy, NY, 2013-05)Alternatively, muscle fibers engineered from mammalian skeletal muscle progenitor cells may provide an additional experimental platform to investigate history-dependent phenomena. Muscle fibers produced in vitro would allow ... -
An embryonic development-inspired, cell-based and scaffold-free method to engineer single fibers for tendon
Schiele, Nathan Robert (Rensselaer Polytechnic Institute, Troy, NY, 2012-05) -
Cell chirality in three-dimensional epithelial tissue morphogenesis
Chin, Amanda S. (Rensselaer Polytechnic Institute, Troy, NY, 2018-08)To investigate inherent cellular chirality in 3D, we developed a dual layered Matrigel system and studied the role of chirality in morphogenesis and tumor development, as well as its mediating factors. Cultivation of ... -
Characterization of the neural stem cell response to extracellular matrix produced by dynamically-stimulated endothelial cells
Ellison, Karen Suzanne (Rensselaer Polytechnic Institute, Troy, NY, 2011-12) -
Developing novel platforms for engineering human tissues
Singh, Gurtej (Rensselaer Polytechnic Institute, Troy, NY, 2012-12) -
Development of bioactive biomaterials for pluripotent stem cell arterial venous differentiation
Dorsey, Taylor Braam (Rensselaer Polytechnic Institute, Troy, NY, 2016-12)Within the framework of this thesis, we proposed to investigate ephrinB2/EphB4 signaling with respect to vascular and arterial venous pluripotent stem cell fate in vitro, specifically utilizing biomaterial approaches to ... -
Direct and indirect endothelial regulation of neural progenitor cells : a modular approach to understand the neural stem cell niche
Dumont, Courtney Margaret (Rensselaer Polytechnic Institute, Troy, NY, 2014-08)The dynamic EC phenotype will produce soluble (cytokines) and insoluble (matrix) fractions that are biochemically distinct from statically produced EC phenotype. NPCs exposed to the dynamic EC-soluble fraction, comprised ... -
Driving arterial vascular differentiation of embryonic stem cells through neuropilin-1
Kim, Diana (Rensselaer Polytechnic Institute, Troy, NY, 2016-05)Characterization of the derived Nrp1+ endothelial progenitor cells (EPCs) reveal that they do indeed express higher levels of many arterial markers, in particular EphrinB2, and lower levels of venous marker, EphB4. ... -
Effects of electrospun fiber diameter on astrocyte morphology and reactivity
Desmond, Gregory (Rensselaer Polytechnic Institute, Troy, NY, 2015-05)A variety of bioengineered scaffolds have previously been fabricated and tested for CNS regeneration following injury. Recent study has examined the effect of these scaffolds on the behavior of astrocytes, demonstrating a ... -
Generation of functional vascular channels using 3D bio-printing technology
Lee, Vivian Kim (Rensselaer Polytechnic Institute, Troy, NY, 2014-05)3D bio-printing technology capable of dispensing live cells, soluble factors, and phase-changing hydrogel in a desired pattern, has great potential in creating 3D tissue. However, maintaining the viability of a thick tissue ... -
High-resolution and high sensitivity mesoscopic fluorescence tomography based on de-scanning EMCCD: system design and thick tissue imaging applications
Öztürk, Mehmet Saadeddin (Rensselaer Polytechnic Institute, Troy, NY, 2016-12)Optical microscopy has been one of the essential tools for biological studies fordecades, however, its application areas was limited to supercial investigation due tostrong scattering in live tissues. Even though advanced ... -
Hydrogels for acute spinal cord injury : physical/chemical material characterization and assessment of astrocytic response
McKay, Christopher Allen (Rensselaer Polytechnic Institute, Troy, NY, 2014-05)Thus, there is a significant need for an efficacious SCI treatment capable of promoting regeneration of lost neuronal connections and restoration of functional motor behavior. A number of biomaterial-based, tissue engineering ... -
Investigation of directed neurite outgrowth mediated by Schwann cell extracellular matrix and adhesion molecules
Seggio, Angela Michele (Rensselaer Polytechnic Institute, Troy, NY, 2010-08) -
Smart bandage for wound healing
Nesbitt, Robert Sterling (Rensselaer Polytechnic Institute, Troy, NY, 2014-05)Chronic wounds, which do not heal in a timely manner like regular wounds, are a serious problem for patients and heath care providers around the world. Chronic wounds may take years to heal, or may never heal at all. They ... -
Static magnetic fields in the regulation of bone cell function and cell differentiation
Leventis, Katerina (Rensselaer Polytechnic Institute, Troy, NY, 2009-05) -
The effects of flow on adhesion molecule expression and monocyte-endothelial interactions in vitro
Abueg, Ellaine (Rensselaer Polytechnic Institute, Troy, NY, 2008-12) -
Tools for rapid screening of 3D composite materials and optimization of cell behavior
Bertucci, Christopher Peter (Rensselaer Polytechnic Institute, Troy, NY, 2016-12)Severe traumatic injuries and disease are major contributors to mortality in the United States and present large health and economic burdens. Organ transplants and autologous grafts are the gold standard treatments for ...