RPI Theses Online (Complete): Recent submissions
Now showing items 21-40 of 3764
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Design and fabrication of the teepee photonic crystal for high-efficiency thin film solar cell architectures
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)The goal of this thesis is to provide the fabrication foundation and analysis of a photonic crystal-based tunnel oxide passivated contact (TOPCon) solar cell. A theoretical framework will be provided that studies the light ... -
Protease-catalyzed synthesis of N-acryloyl-oligopeptides and histidine-containing oligopeptides
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)Synthetic peptides, peptides built via chemical methodology or through recombinant technology, have been designed for use in therapeutics. Current chemical methods to create synthetic peptides rely largely on solid-phase ... -
Development of experimental and analytical methods for low-rate (α,n) neutron source characterization
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)The production of (α,n) neutrons occurs intrinsically for many important nuclear materials which contain actinide species and low-mass nuclides. Actinides are fundamentally radioactive due to instability caused by their ... -
Drug discovery for Alzheimer's disease targeting the transmembrane domain of amyloid precursor protein (AAPTM).
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)Alzheimer’s Disease (AD) is a neurological disease currently affecting close to 6 million Americans (3). A major neuropathological hallmark of AD is the presence of senile plaques in the cerebral cortex and hippocampus ... -
Using Milkyway@home to measure the mass of the orphan-chenab stream progenitor dwarf galaxy
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)We fit the mass and radial profile of the Orphan-Chenab Stream's (OCS) dwarf galaxy progenitor by using turnoff stars in the Sloan Digital Sky Survey (SDSS) and the Dark Energy Camera (DEC) to constrain N-body simulations ... -
Privacy preservation and evaluation in machine learning
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)This thesis aims at improving methods for preserving privacy in machine learning for both generative and predictive models, and evaluating the privacy lost. Creating useful machine learning models requires the use of ... -
Comprehensive, explainable, ml-based molecular toxicity and protein-ligand binding predictions
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)Machine Learning (ML) and computer aided drug design have widely been considered to accelerate and focus the time-consuming and costly drug discovery process. In this work, we have used ML tools to improve early-stage drug ... -
Dynamics of individual learning
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)This work focuses on understanding how individuals learn complex tasks. Most real-world tasks that we learn and need help with, are complex. Yet most of our knowledge about human learning is based on simple tasks. We think ... -
A methodology to evaluate equity in resource accessibility
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)Inequalities present in society have been of increased interest in recent years, particularly in the United States. One source of inequality is unequal access to important resources, such as shopping. Recent developments ... -
Tackling health inequity using machine learning fairness, AI, and optimization
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)Health inequity, which leads to unfair and preventable disparities across individuals in opportunities to achieve optimal health, has been brought back into the national spotlight by global COVID-19 pandemic. As artificial ... -
Low-order methods for nonconvex functional constrained optimization
(Rensselaer Polytechnic Institute, Troy, NY, 2022-07)Recently, many real-world problems in engineering and data science not only have very large scales and complicated functional constraints, but also go beyond the scope of convex optimization and inevitably include nonconvex ... -
Shortest path network interdiction under uncertainty
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)This research considers three extensions of the shortest path network interdiction problem to protect against parameter uncertainty. The shortest path interdiction problem is a game of two players with conflicting agendas ... -
Dynamic methods for matching requests to suppliers in transportation platforms
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)Peer-to-peer transportation platforms dynamically match requests (e.g., a ride, a delivery) to independent suppliers. A central challenge is how to make these matching decisions that can accommodate the different needs ... -
Characterization of glycan-protein interactions in SARS-CoV-2 and Parkinson's disease
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)ABSTRACT. Heparan sulfate (HS) acts as a co-receptor of angiotensin-converting enzyme 2 (ACE2) by interacting with severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein (SGP), facilitating ... -
Building integrated agriculture simulation (BIA-sim) development of a simulation based software for the implementation of building integrated agriculture in urban contexts
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)Since the world's population is growing at an alarming rate, scientists and researchers are trying to find ways to increase both the quality and quantity of food available. However, the current methods used in the agriculture ... -
Automatic vectorization for multi-party computation
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)We introduce a new compiler for multi-party computation (MPC) which performs backend-independent optimizations over the MPC Source intermediate representation and outputs C++ code using the MOTION framework for MPC. We ... -
Using diffusion equation model to analyze advanced sound energy decay in reverberation chamber
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)In the room acoustics measurement process, a non-diffused sound field is neglected in conventional chamber-based studies of absorbing materials, which reduces accuracy and can even produce inconsistent results. An additional ... -
A study of the flow physics on a swept wing and the application of steady blowing to separation control
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)An experimental study was conducted to understand the effect of steady blowing from segmented jets along the leading edge of a 30° swept wing with an aspect ratio of approximately 4, with a twist of approximately −2.5° ... -
Elucidating the role of multimodal ligand surfaces in protein chromatography using molecular dynamics simulations
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)Over the past several years, protein-based therapeutics have revolutionized the pharmaceutical industry, with applications for treatment of a range of diseases from autoimmune to cancer. This rise has been accompanied by ... -
Essays in supply chain risk management : an analytical and networks perspective
(Rensselaer Polytechnic Institute, Troy, NY, 2022-08)In the last few decades, a number of organizations have been affected by unforeseen supply-chain vulnerabilities and disruptions. A common theme at the heart of these crises is the lack of robust processes to identify and ...