Browsing RPI Theses Open Access by Author "Wan, Leo Q."
Now showing items 1-8 of 8
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MRI classification of cartilage degradation
Fleck, Allison Kathleen McEntee (Rensselaer Polytechnic Institute, Troy, NY, 2018-12)This research furthers our understanding of the MR evaluation of articular cartilage and reveals the necessity of considering zonal-dependent properties of articular cartilage. Furthermore, combining zonal analyses and ... -
MRI-based strain mapping for cartilage repair assessment
Sajid, Sameer (Rensselaer Polytechnic Institute, Troy, NY, 2021-05)I conclude that MRI-based strains should be considered for cartilage repair evaluation. The mean strains of both the interface and regions of altered material properties correlated with mechanical stiffness changes. As a ... -
Non-canonical cell stress in osteogenesis imperfecta
Gorrell, Laura (Rensselaer Polytechnic Institute, Troy, NY, 2021-05)We used this model to demonstrate noncanonical quality control of PC1 folding. Like other secretory proteins, PC1 misfolds and accumulates in the lumen of endoplasmic reticulum (ER), disrupting the function of this crucial ... -
System-wide advances in photon-counting CT : corrections, simulations, and image analysis
Getzin, Matthew (Rensselaer Polytechnic Institute, Troy, NY, 2019-12)Imaging plays a major role in biomedicine with X-ray computed tomography (CT) as a primary example. X-ray CT becomes increasingly popular since its invention in the 1970’s, now reaching over 100 million scans yearly ... -
Task analysis for rigid scope natural orifice translumenal endoscopic surgery (NOTES) cholecystectomy
Nemani, Arun (Rensselaer Polytechnic Institute, Troy, NY, 2012-12) -
The influence of mechanical stimulation and macromolecular crowding on engineered, scaffold-free tendon fibers
Mubyana, Kuwabo (Rensselaer Polytechnic Institute, Troy, NY, 2018-05)The current standard for treatment of high grade tendon tears is surgical replacement grafts, however they present the challenge of limited tissue availability (allografts and autografts), donor site morbidity (autografts), ... -
Toward development of a cell-derived engineered synovial fluid for protection of cartilage matrix
Abu-Hakmeh, Ahmad Emad (Rensselaer Polytechnic Institute, Troy, NY, 2018-08)Osteoarthritis (OA) is an irreversible degenerative joint disease characterized by low-grade inflammation, mechanical inferiority, and structural changes to the various joint tissues. At the center of OA progression is the ... -
Toward development of a potassium (K+)-based intra-articular injection for osteoarthritis treatment
Erndt-Marino, Joshua Dean (Rensselaer Polytechnic Institute, Troy, NY, 2018-05)Osteoarthritis (OA) is characterized by a slow progression of cartilage erosion driven in part by a cascade of inflammatory mediators produced from an activated synovium and the cartilage itself. Chondrocytes lose their ...