For amyloidogenic peptides, their adverse health effects are primarily derived from their ability to aggregate into small oligomers and subsequently large fibrils. Here, an aggrega-tion reaction model is developed in order ...

The model equations are refined to expand its failure prediction capabilities. The electron temperature is re-defined solely as a function of the electric field, and the defect generation rate is more closely aligned with ...

With a need for greener fuels, research into production of biofuels is essential. Isobutanol out preforms ethanol in key metrics such as engine compatibility, energy density, and gasoline blending. Current biofuel strategies ...

Over the past several years, protein-based therapeutics have revolutionized the pharmaceutical industry, with applications for treatment of a range of diseases from autoimmune to cancer. This rise has been accompanied by ...

Two-dimensional (2D) transition metal dichalcogenides (TMDCs) represent a new class of atomically thin semiconductors with superior optical and optoelectronic properties. TMDCs have extensively been investigated for potential ...

Chondroitin sulfate (CS) is an important glycosaminoglycan that is predominantly present in cartilage and the surfaces of many cells and extracellular matrices. It has been widely used in treating osteoarthritis due to its ...

Drug development is inefficient and expensive, with less than 10% of drug candidates entering clinical trials proceeding to market, and each costing an estimated $2.5 billion. This inefficiency is due to several reasons, ...

In the first approach, a multiscale platform for the discovery of peptide affinity chromatography ligands was developed and applied for the purification of human growth hormone (hGH) from yeast cultures. A high-throughput ...