Now showing items 1-13 of 13

    • DeFi Survival Analysis: Insights into Risks and User Behavior 

      Green, Aaron; Cammilleri, Christopher; Erickson, John S.; Seneviratne, Oshani; Bennett, Kristin (Springer, 2022-06)
      We propose a decentralized finance (DeFi) survival analysis approach for discovering and characterizing user behavior and risks in lending protocols. We demonstrate how to gather and prepare DeFi transaction data for ...
    • Making Study Populations Visible through Knowledge Graphs 

      Chari, Shruthi; Qim, Miao; Agu, Nkechinyere; Seneviratne, Oshani; McCusker, Jamie; Bennett, Kristin; Das, Amar; McGuinness, Deborah L. (2019-10-12)
    • Ontology-enabled Analysis of Study Populations 

      Chari, Shruthi; Qim, Miao; Agu, Nkechinyere; Seneviratne, Oshani; McCusker, Jamie; Bennett, Kristin; Das, Amar; McGuinness, Deborah L. (2019-10-01)
      We address the problem of modeling study populations in research studies in a declarative manner. Research studies often have a great degree of variability in the reporting of population descriptions. To make study populations ...
    • Semantically-targeted analytics for reproducible scientific discovery 

      New, Alexander; Chari, Shruthi; Qim, Miao; Rashid, Sabbir; Erickson, John S.; McGuinness, Deborah L.; Bennett, Kristin (2019-05-13)
      We develop a semantics-driven, automated approach for dynamically performing rigorous scientific studies. This framework may be applied to a wide variety of data and study types; here, we demonstrate its suitability for ...
    • Identifying Windows of susceptibility by temporal Gene Analysis 

      Bennett, Kristin; Brown, Elisabeth; De Los Santos, Hannah; Poegel, Matt; Kiehl, Thomas; Patton, Evan; Norris, Spencer; Temple, Sally; Erickson, John S.; McGuinness, Deborah L.; Boles, Nathan (Scientific Reports, 2019-02-01)
      Increased understanding of developmental disorders of the brain has shown that genetic mutations, environmental toxins and biological insults typically act during developmental windows of susceptibility. Identifying these ...
    • Semantically-aware population health risk analyses 

      New, Alexander; Rashid, Sabbir; Erickson, John S.; McGuinness, Deborah L.; Bennett, Kristin (arXiv, 2018-11-27)
      One primary task of population health analysis is the identification of risk factors that, for some subpopulation, have a significant association with some health condition. Examples include finding lifestyle factors ...
    • Ontology-enabled Breast Cancer Characterization 

      Seneviratne, Oshani; Rashid, Sabbir; Chari, Shruthi; McCusker, Jamie; Bennett, Kristin; Hendler, James A.; McGuinness, Deborah L. (2018-10-01)
      We address the problem of characterizing breast cancer, which today is done using staging guidelines. Our demo will show different breast cancer staging results that leverage the Whyis semantic nanopublication knowledge ...
    • The Whyis Knowledge Graph Framework in Action 

      McCusker, Jamie; Rashid, Sabbir; Agu, Nkechinyere; Bennett, Kristin; McGuinness, Deborah L. (2018-10-01)
      We will demonstrate a reusable framework for developing knowledge graphs that supports general, open-ended development of knowledge curation, interaction, and inference. Knowledge graphs need to be easily maintainable and ...
    • Knowledge Integration for Disease Characterization: A Breast Cancer Example 

      Seneviratne, Oshani; Rashid, Sabbir; Chari, Shruthi; Bennett, Kristin; Hendler, James A.; McGuinness, Deborah L. (2018-07-20)
      With the rapid advancements in cancer research, the information that is useful for characterizing disease, staging tumors, and creating treatment and survivorship plans has been changing at a pace that creates challenges ...
    • Developing Scientific Knowledge Graphs Using Whyis 

      McCusker, Jamie; Rashid, Sabbir; Agu, Nkechinyere; Bennett, Kristin; McGuinness, Deborah L. (CEUR Workshop Proceedings, 2018)
      We present Whyis, the first framework for creating custom provenance-driven knowledge graphs. Whyis knowledge graphs are based on nanopublications, which simplifies and standardizes the production of structured, ...
    • Window of Susceptibility for Zika-Induced Microcephaly Identified by Temporal Gene Analysis 

      Bennett, Kristin; Brown, Elisabeth; De Los Santos, Hannah; Poegel, Matt; Kiehl, Thomas; Patton, Evan; McGuinness, Deborah L.; Temple, Sally; Boles, Nathan (2017-04-10)
      Increased understanding of developmental disorders of the brain has shown that genetic mutations, environmental toxins and biological insults typically act during developmental windows of susceptibility. Through analysis ...
    • SemNExT: A Framework for Semantically Integrating and Exploring Numeric Analyses 

      Patton, Evan; Brown, Elisabeth; Poegel, Matt; De Los Santos, Hannah; Fasano, Christopher; Bennett, Kristin; McGuinness, Deborah L. (2015-10-11)
      Combining statistical techniques with semantic data representations holds the potential to enhance understandability of scientific results. It can augment scientific findings with existing data sources in a reproducible ...
    • Integrating Semantics and Numerics: Case Study on Enhancing Genomic and Disease Data Using Linked Data Technologies 

      McGuinness, Deborah L.; Bennett, Kristin (2015-08-18)
      Bioinformatics was an early adopter of semantic technologies and provided many ontologies and datasets in semantic formats to aid integration of biological and biochemical data. There is a lack of tooling support however ...