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    • Differences in Cancer Phenotypes Among Frequent CHEK2 Variants and Implications for Clinical Care—Checking CHEK2 

      Bychkovsky, Brittany L; Agaoglu, Nihat B; Horton, Carolyn; Zhou, Jing; Yussuf, Amal; Hemyari, Parichehr; Richardson, Marcy E; Young, Colin; LaDuca, Holly; McGuinness, Deborah L.; Scheib, Rochelle; Garber, Judy E; Rana, Huma Q (JAMA Oncol., 2022-09-22)
      Importance Germline CHEK2 pathogenic variants (PVs) are frequently detected by multigene cancer panel testing (MGPT), but our understanding of PVs beyond c.1100del has been limited. Objective To compare cancer phenotypes ...