Browsing The Linhardt Research Labs by Title
Now showing items 395-414 of 1022
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Fast preparation of RG-I enriched ultra-low molecular weight pectin by an ultrasound accelerated Fenton process
(Nature, 2017-12-01)Pectin, a natural polysaccharide found in the cell wall of most higher plant such as citrus, has drawn much attention due to its potential beneficial role in facilitating the treatment of many diseases like cancer, hyper ... -
Fast preparation of rhamnogalacturonan I enriched low molecular weight pectic polysaccharide by ultrasonically accelerated metal-free Fenton reaction
(2019-10-01)The recovery of pectic polysaccharides with high rhamnogalacturonan I (RG-I) branches from citrus canning processing water was achieved in a previous study aimed at reducing chemical oxygen demand and benefiting both process ... -
Fermented cassava residue lignin prepared by sequential acid steam-explosion and hot-alkaline treatment and its antioxidant properties
(2020-11-01)Fermented cassava residue (FCR) is a solid waste generated in cassava-based ethanol production that constitutes a major environmental challenge and wastes a natural resource. In the present study, a process involving ... -
FGF-FGFR signaling mediated through glycosaminoglycans in microtiter plate and cell-based microarray platforms
(2013-12-17)Fibroblast growth factor (FGF) signals cell growth through its interaction with a fibroblast growth factor receptor (FGFR) and a glycosaminoglycn (GAG) coreceptor. Here, we examine the signaling of five different FGFs (1, ... -
Fibroblast growth factor signaling mediates pulmonary endothelial glycocalyx reconstitution
(2017-06-01)The endothelial glycocalyx is a heparan sulfate (HS)-rich endovascular structure critical to endothelial function. Accordingly, endothelial glycocalyx degradation during sepsis contributes to tissue edema and organ injury. ... -
Fibroblast growth factor-based signaling through synthetic heparan sulfate block copolymers studied using high-cell density 3D cell printing
(The American Society for Biochemistry and Molecular Biology (ASBMB) and Elsevier, 2014)Four well-defined heparan sulfate (HS) block copolymers containing S-domains (high sulfo group content) placed adjacent to N-domains (low sulfo group content) were chemoenzymatically synthesized and characterized. The ... -
Filter-entrapment enrichment pull-down assay for glycosaminoglycan structural characterization and protein interaction
(Elsevier, 2020-10-01)Heparins are the most pharmaceutically important polysaccharides. These heparin-based anticoagulant/antithrombotic agents include unfractionated heparins, low molecular weight heparins (LMWHs) and ultralow molecular weight ... -
Flexible electrospun cellulose fibers as an affinity packing material for the separation of bovine serum albumin
(2011)Flexible, well-dispersed and continuous 100-nm diameter cellulose fibers were prepared from an ionic liquid solvent by a novel dry-jet wet-electrospinning process. The ribbon fibers formed were chemically activated and an ... -
Flexible Nanocomposite Thin Film Energy Storage Devices
(2007)There is strong recent interest in ultrathin, flexible, safe energy storage devices to meet the various design and power needs of modern gadgets. To build such fully flexible and robust electrochemical devices, multiple ... -
Fluorous-assisted chemoenzymatic synthesis of heparan sulfate oligosaccharides
(American Chemical Society (ACS), 2014-04-18)Fluorous-assisted chemoenzymatic synthesis of heparan sulfate oligosaccharides -
Fractionation of Heparin-Derived Oligosaccharides by Gradient Polyacrylamide-Gel Electrophoresis
(1987-01-01)Heparin-derived oligosaccharides, prepared by using flavobacterial heparinase, having a high degree of heterogeneity (sequence variability) were resolved into sharp well-defined bands by using polyacrylamide gel electrophoresis ... -
Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties
(Elsevier, 2022-05-01)Sulfation pattern and molecular weight (MW) play a key role in the biological actions of sulfated glycans. Besides anticoagulant effects, certain sulfated glycans can also exhibit anti-SARS-CoV-2 properties. To develop a ... -
Fucosylated chondroitin sulfate 9-18 oligomers exhibit molecular size-independent potent antithrombotic activity during circulating in the blood
(2020)Fucosylated chondroitin sulfate (FCS) oligosaccharides extracted from sea cucumber and depolymerized exhibit potent anticoagulant activity. Knowledge of the antithrombotic activity of different size oligosaccharides and ... -
Fucosylated chondroitin sulfate from Isostichopus badionotus alleviates metabolic syndromes and gut microbiota dysbiosis induced by high-fat and high-fructose diet
(2019-03-01)Fucosylated chondroitin sulfate from Isostichopus badionotus (fCS-Ib) is a kind of sulfated polysaccharides with well-repeated structure. In our former publications, fCS-Ib has been reported to be a functional food ingredient ... -
Fucosylated chondroitin sulfate oligosaccharides exert anticoagulant activity by targeting at intrinsic tenase complex with low FXII activation: importance of sulfation pattern and molecular size
(2017-01-01)Fucosylated chondroitin sulfates (fCSs) are structurally unusual glycosaminoglycans isolated from sea cucumbers that exhibit potent anticoagulant activity. These fCSs were isolated from sea cucumber, Isostichopus badionotus ... -
Fucosylated chondroitin sulfate oligosaccharides from Isostichopus badionotus regulates lipid disorder in C57BL/6 mice fed a high-fat diet
(2018-12-01)Fucosylated chondroitin sulfate (fCS) and its depolymerized derivative (DfCS), prepared from sea cucumbers, are well-known for their anticoagulant activity. However, their other functional activities are poorly understood. ... -
Full recovery of value-added compounds from citrus canning processing water
(2018-03-01)In the production of canned citrus, large amounts of processing water were discharged during the segment membrane removal process, causing severe pollution. In order to reduce pollution and recover the bioactive compounds ... -
Functional chondroitin sulfate from Enteroctopus dofleini containing a 3-O-sulfo glucuronic acid residue
(2015-08-24)There are several reports that chondroitin sulfate containing K-type units [GlcA (3S)-GalNAc (4S)] exhibiting similar levels of neurite outgrowth promoting activities as CS having high amounts of B-, D- and E-type disulfated ... -
Functional role of glycosaminoglycans in decellularized lung extracellular matrix
(Elsevier, 2020-01-15)Despite progress in use of decellularized lung scaffolds in ex vivo lung bioengineering schemes, including use of gels and other materials derived from the scaffolds, the detailed composition and functional role of ... -
Functionalization of electrospun nanofibers and fiber alignment enhance neural stem cell proliferation and neuronal differentiation
(Frontiers Media SA, 2020-10-26)Neural stem cells (NSCs) have the potential to generate the cells of the nervous system and, when cultured on nanofiber scaffolds, constitute a promising approach for neural tissue engineering. In this work, the impact of ...