Browsing The Linhardt Research Labs by Title
Now showing items 574-593 of 1022
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Ionic Liquid Solvent Properties as Predictors of Lignocellulose Pretreatment Efficacy
(2010-11-03)Effective pretreatment of lignocellulosic biomass is vital to its bioconversion to a usable liquid fuel. A growing body of work has focused on using room temperature ionic liquids (RTILs) to pretreat lignocellulose for ... -
Ionic liquid-mediated selective extraction of lignin from wood leading to enhanced enzymatic cellulose hydrolysis
(2009-04-01)Lignocellulose represents a key sustainable source of biomass for transformation into biofuels and bio-based products. Unfortunately, lignocellulosic biomass is highly recalcitrant to biotransformation, both microbial and ... -
Ionic Liquids In Carbohydrate Chemistry – Current Trends And Future Directions
(2005-10-01)Room Temperature Ionic Liquids (RTILs) have recently been introduced as new solvents in the chemical and biotechnological arenas. Carbohydrates are important natural products that play important biological and commercial ... -
Is Human Placenta Proteoglycan Remodeling Involved in Pre-Eclampsia?
(Springer, 2008)Impaired placento-fetal communication is a coherent symptom of exaggerated pre-eclampsia. The impact of the cellular expression of different glycosaminoglycans (GAGs) in this event on the placenta in pre-eclampsia is still ... -
Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure
(The American Society for Biochemistry and Molecular Biology (ASBMB) and Elsevier, 2020-12-25)Infiltration of peripheral immune cells after blood-brain barrier dysfunction causes severe inflammation after a stroke. Although the endothelial glycocalyx, a network of membrane-bound glycoproteins and proteoglycans that ... -
Isoflavonoid Production by Genetically Engineered Microorganisms
(2013-01-01)Isoflavonoids are a class of plant natural products gaining attention due to their pharmaceutical properties. These natural compounds constitute a subclass of flavonoids, which belong to a broader class of plant products ... -
Isoflavonoid production by genetically engineered microorganisms
(2013-01-01)Isoflavonoids are a class of plant natural products gaining attention due to their pharmaceutical properties. These natural compounds constitute a subclass of flavonoids, which belong to a broader class of plant products ... -
Isolation and Characterization of b-Cyclodextrin Sulfates by Preparative Gradient Polyacrylamide Gel Electrophoresis,Capillary Electrophoresis and Electrospray Ionization Mass Spectrometry
(1998)A beta-cyclodextrin sulfate mixture has been fractionated using discontinuous gradient polyacrylamide gel electrophoresis. Semidry electrotransfer of the sample onto a positively charged nylon membrane and visualization ... -
Isolation and Characterization of Heparan Sulfate from Crude Porcine Intestinal Mucosa Peptidoglycan Heparin
(1995)A method for the preparation of heparan sulfate from peptidoglycan heparin is described. The objective of this research was to provide a basis for the development and validation of an industrial process to support the ... -
Isolation and Characterization of Heparan Sulfate from Various Murine Tissues
(Springer, 2006-11-01)Heparan sulfate (HS), is a proteoglycan (PG) found both in the extracellular matrix and on cell surface. It may represent one of the most biologically important glycoconjugates, playing an essential role in a variety of ... -
Isolation and Characterization of Raw Heparin from Dromedary Intestine: Evaluation of a New Source of Pharmaceutical Heparin
(2003-01-01)Heparin, a heterogeneous anionic polysaccharide, is the glycosaminoglycan (GAG) used clinically an anticoagulant. This anticoagulant activity is primarily derived from its binding to the serine protease inhibitor antithrombin ... -
Isolation and Recovery of Acidic Oligosaccharides from Polyacrylamide Gels by Semi-Dry Electrotransfer
(1990-01-01)Acidic oligosaccharides derived from glycosaminoglycan heparin were separated by polyacrylamide gradient gel electrophoresis (PAGE). The gel could be visualized using Alcian Blue dye to give a pattern of highly resolved, ... -
Isolation and structural characterization of glycosaminoglycans from heads of red salmon (Oncorhynchus nerka)
(Jacobs, 2014)Glycosaminoglycans (GAGs) are linear, highly negatively charged polysaccharides. They are ubiquitous molecules exhibiting a wide range of biological functions with numerous applications in pharmaceutical, cosmetic, and ... -
Isolation of a lectin binding rhamnogalacturonan-I containing pectin from pumpkin
(2017)A rhamnogalacturonan-I (RG-I) containing pectic polysaccharide (PPc) was isolated from pumpkin following a low-temperature alkali treatment and a combination of gradual alcohol precipitation and ion-exchange. Monosaccharide ... -
Isolation of bovine corneal keratan sulfate and its growth factor and morphogen binding
(FEBS Press, 2013-05-01)Keratan sulfate (KS) is an important glycosaminoglycan that is found in cartilage, reproductive, and neural tissues. Corneal KS glycosaminoglycan is found N-linked to lumican, keratocan, and mimecan proteoglycans and has ... -
Kartogenin-loaded coaxial PGS/PCL aligned nanofibers for cartilage tissue engineering
(2020-02-01)Electrospinning is a valuable technology for cartilage tissue engineering (CTE) due to its ability to produce fibrous scaffolds mimicking the nanoscale and alignment of collagen fibers present within the superficial zone ... -
Keratan sulfate glycosaminoglycan from chicken egg white
(2016-07-01)Keratan sulfate (KS) was isolated from chicken egg white in amounts corresponding to ∼0.06 wt% (dry weight). This KS had a weight-average molecular weight of ∼36–41 kDa with a polydispersity of ∼1.3. The primary repeating ... -
Kinetic and Structural Studies on Interactions between Heparin/GAGs and Langerin
(2016)Langerin, a C-type lectin, is expressed in Langerhans cells. It was reported that langerin binds sulfated glycans, which is an important initial step for its role in blocking human immunodeficiency virus (HIV) transmission ... -
Kinetic and Structural Studies on Interactions between Heparin/Heparan Sulfate and Proteins of the Hedgehog Signaling Pathway
(American Chemical Society (ACS), 2007-04-03)Heparan sulfate (HS) proteoglycans (PGs) interact with a number of extracellular signaling proteins, thereby playing an essential role in the regulation of many physiological processes. These interactions are important for ... -
Kinetic Studies on the Interaction of Heparin and Complement Proteins using Surface Plasmon Resonance
(Elsevier, 2005-11-15)Heparin is a naturally occurring polysaccharide known to interact with complement proteins and regulate multiple steps in the complement cascade. Quantitative information, in the form of affinity constants for heparin-complement ...