Browsing Linhardt Research Labs Papers by Title
Now showing items 117-136 of 1022
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C-2 Epimerization of N-Acetylglucosamine in an Oligosaccharides Derived from Heparan Sulfate
(1996-01-01)The isolation of a heparan sulfate derived tetrasaccharide containing N-acetylmannosamine is described. The N-acetylmannosamine residue at the reducing terminus of heparin lyase derived tetrasaccharide is formed by base ... -
Can natural fibers be a silver bullet? Antibacterial cellulose fibers through covalent bonding of silver nanotparticles to electrospun fibers
(2016)Natural cotton was dissolved in a room-temperature ionic liquid 1-ethyl-3-methyl acetate and wet-jet electrospun to obtain nanoscale cotton fibers with a substantially reduced diameter—and therefore an increased surface ... -
Candida auris mannans and pathogen-host interplay
(2020-12-01)Candidaauris, amultidrug-resistant fungal pathogen, is re-sponsible for the recent globaloutbreaks in hospitalized andlong-term care patients with signifi-cant mortality. A new study byBrunoet al.delineates innatehost ... -
Capillary Affinity Chromatography and Affinity Capillary Electrophoresisof Heparin Binding Proteins
(1998)A new approach for separation, capillary affinity chromatography, is introduced for studying the interaction of heparin with antithrombin III and secretory leukocyte proteinase inhibitor. Heparin is covalently immobilized ... -
Capillary Electrophoresis for Monitoring Chemical Reactions: Sulfation and Synthetic Manipulation of Sulfated Carbohydrates
(1995-02-01)The lack of a simple and rapid method for the analysis of structurally similar, highly charged, carbohydrates has made monitoring their chemical modification much more difficult than in traditional synthetic reactions where ... -
Capillary Electrophoresis for the Analysis of Chondroitin Sulfate and Dermatan Sulfate-Derived Disaccharides
(1991-05-15)High-voltage capillary zone electrophoresis (CZE) has been used for the first time in the analysis of non-, mono-, di-, and trisulfated disaccharides derived from chondroitin sulfate, dermatan sulfate, and hyaluronic acid. ... -
Capillary electrophoresis for the analysis of glycosaminoglycan-derived disaccharides
(2013-01-01)A quantitative and highly sensitive method for the analysis of glycosaminoglycan (GAG)-derived disaccharides is presented that relies on capillary electrophoresis (CE) with laser-induced fluorescence (LIF) detection. This ... -
Capillary Electrophoresis for the Analysis of Glycosaminoglycans and Glycosaminoglycan-Derived Oligosaccharides
(Wiley, 2002-03-20)Capillary electrophoresis is a common technique used for glycosaminoglycan-derived disaccharide analysis because of its high resolving power, high separation efficiency, high sensitivity, short analysis time, and straightforward ... -
Capillary electrophoresis for total glycosaminoglycan analysis
(2014-01-01)A capillary zone electrophoresis-laser induced fluorescence detection (CZE-LIF) method was developed for the simultaneous analysis of disaccharides derived from heparan sulfate, chondroitin sulfate/dermatan sulfate, ... -
Capillary Electrophoresis of Complex Natural Polysaccharides
(Wiley, 2008-08-01)Complex natural polysaccharides, glycosaminoglycans (GAGs), are a class of ubiquitous macromolecules that exhibit a wide range of biological functions and participate and regulate multiple cellular events and (patho)physiological ... -
Capillary Electrophoresis of Oligosaccharides
(1994)This chapter reports an overview of the recent advances in the analysis of mono- and oligosaccharides by capillary electrophoresis (CE); furthermore, relevant reviews and research articles recently published in the field ... -
Capillary Electrophoresis to Measure Sulfoesterase Activity on Chondroitin Sulfate and Heparin Derived Disaccharides
(1993)Capillary electrophoresis was used to assay sulfoesterase activity on sulfated disaccharides derived from chondroitin sulfate, dermatan sulfate and heparin. The three sulfoesterases studied were chondro-4-O-sulfatase (EC ... -
Capillary Electrophoresis-Mass Spectrometry for the Analysis of Heparin Oligosaccharides and Low Molecular Weight Heparin
(2016-02-02)Heparins, highly sulfated, linear polysaccharides also known as glycosaminoglycans, are among the most challenging biopolymers to analyze. Hyphenated techniques in conjunction with mass spectrometry (MS) offer rapid analysis ... -
Capillary Zone Electrophoresis for the Quantitation of Oligosaccharides Formed Through the Action of Chitinase
(1991-01-01)Capillary zone electrophoresis with fluorescence detection was used to analyze the products formed by chitinase acting on N-acetylchitooligosaccharide-fluorescent conjugates. Six oligosaccharides of the structure ... -
Carbohydrate Analysis of Glycoproteins
(1990)Many of the products prepared by biotechnological approaches, including recombinant genetic engineering, cell tissue culture, and monoclonal technologies, are glycoproteins. As little as five years ago, glycosylation was ... -
Carbohydrate-containing molecules as potential biomarkers in colon cancer
(2014-04-01)Glycans play a critical role in physiological and pathological processes through interaction with a variety of ligands. Altered expression and dysregulation of these molecules can cause aberrant cellular function such as ... -
Carbohydrate-Protein Interactions in Vascular Biology
(1995-01-01)Carbohydrate-protein interactions participate in a wide variety of biological and pathological events. In recent years, particular attention has been paid to the carbohydrate-protein interactions that occur in vascular ... -
Carbon Inhibits VEGF and FGF Promoted Angiogenesis
(FEBS Press, 2007)Angiogenesis is important for normal growth and wound healing processes. An imbalance of the growth factors involved in this process, however, causes the acceleration of several diseases including malignant, ocular, and ... -
Carrageenan-induced increase in interleukin-8 secretion is modified by pre-treatment with galactosidases and carrageenases
(Elsevier, 2010)The common food additive carrageenan predictably induces intestinal inflammation in animal models. Mechanisms of carrageenan-induced NFκB and IL-8 stimulation include an immune-mediated pathway involving toll-like receptor ... -
Catalytic mechanism of heparinase II revealed by site-directed mutagenesis and the crystal structure with its substrate
(Elsevier, 2010)Heparinase II (HepII) is an 85-kDa dimeric enzyme that depolymerizes both heparin and heparan sulfate glycosaminoglycans through a β-elimination mechanism. Recently, we determined the crystal structure of HepII from ...