Browsing Linhardt Research Labs Papers by Author "Bai, Zhonghu"
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Characterization and application of a putative transcription factor SUT2 in Pichia pastoris
Yang, Yankun; Zheng, Yating; Wang, Pengcheng; Li, Xiang; Zhan, Chunjun; Linhardt, Robert J.; Zhang, Fuming; Liu, Xiuxia; Zhan, Jinling; Bai, Zhonghu (2020-09-01)Pichia pastoris is able to metabolize methanol via a specific MUT (methanol utilization) pathway. Based on the powerful AOX1 (Alcohol Oxidase 1) promoter, the P. pastoris expression system has become one of the most widely ... -
Identification, Repair and Characterization of a Benzyl Alcohol-Inducible Promoter for Recombinant Proteins Overexpression in Corynebacterium glutamicum
Liu, Xiuxia; Zhao, Zihao; Dong, Guibin; Li, Ye; Peng, Feng; Liu, Chunli; Zhang, Fuming; Linhardt, Robert J.; Yang, Yankun; Bai, Zhonghu (2020-11-01)Corynebacterium glutamicum is an important industrial organism for the production of a variety of biological commodities. We discovered a promoter encoded by the gene NCgl2319 in C. glutamicum, which could be induced by ... -
MAPK/HOG signaling pathway induced stress-responsive damage repair a mechanism for Pichia pastoris to survive from hyperosmotic stress
Wang, Rongbin; Zhao, Tianyu; Zhuo, Junlin; Zhan, Chunjun; Zhang, Fuming; Linhardt, Robert J.; Bai, Zhonghu; Yang, Yankun (2021-02-01)Abstract BACKGROUND MAPK/HOG signaling pathway plays a key role in the response of yeast to external hyperosmotic stress. Over the past few decades, the regulation mechanism for this pathway in the robust yeast, Saccharomyces ...