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    • Strong reduction of the chain rigidity of hyaluronan by selective binding of Ca2+ ions 

      Giubertoni, G.; Pérez de Alba Ortíz, A.; Bano, F.; Zhang, X.; Linhardt, Robert J.; Green, D.E.; DeAngelis, P.L.; Koenderink, G.H.; Richter, R.P.; Ensing, B.; Bakker, H.J. (American Chemical Society (ACS), 2021-02-09)
      The biological functions of natural polyelectrolytes are strongly influenced by the presence of ions, which bind to the polymer chains and thereby modify their properties. Although the biological impact of such modifications ...