Browsing Linhardt Research Labs Papers by Author "Caldwell, E.E.O."
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Differences in the Interaction of Heparin with Arginine and Lysine and the Importance of Basic Amino Acids in the Binding of Heparin to aFGF
Fromm, J.R.; Hileman, R.E.; Caldwell, E.E.O.; Weiler, J.M.; Linhardt, Robert J. (1995)Although the interaction of proteins with glycosaminoglycans (GAGs) such as heparin are of great importance, the general structural requirements for protein- or peptide-GAG interaction have not been well characterized. ... -
Importance of Basic Amino Acids in Heparin and Heparan Sulfate Protein Binding Sites
Caldwell, E.E.O.; Nadkarni, V.D.; Fromm, J.R.; Linhardt, Robert J.; Weiler, J.M. (1996)Heparin and heparan sulfate bind a variety of proteins and peptides to regulate many biological activities. Past studies have examined a limited number of established heparin binding sites and have focused on basic amino ... -
Pattern and Spacing of Basic Amino Acids in Heparin Binding Sites
Fromm, J.R.; Hileman, R.E.; Caldwell, E.E.O.; Weiler, J.M.; Linhardt, Robert J. (1997-07-01)Glycosaminoglycan (GAG)-protein interactions regulate a myriad of physiologic and pathologic processes, yet an understanding of how these molecules interact is lacking. The role of the pattern and spacing of basic amino ... -
Preparation and Biological Activity of N-Sulfated Chondroitin and Dermatan Sulfate Derivatives
Nadkarni, V.D.; Toida, T.; VanGorp, C.L.; Schubert, R.L.; Weiler, J.M.; Hansen, K.P.; Caldwell, E.E.O.; Linhardt, Robert J. (1996)Chondroitin and dermatan sulfates are families of structurally complex, sulfated, linear polysaccharides called glycosaminoglycans (GAGs) with alternating uronic acid and N-acetylated D-galactosamine residues [ 1] (Scheme ...