Browsing Linhardt Research Labs Papers by Author "Caldwell, Elizabeth E.O."

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    • Expression of C1 Esterase Inhibitor by the Baculovirus Expression System: Preparation, Purification and Characterization 

      Wolff, Michael W.; Zhang, Fuming; Roberg, Jeff J.; Caldwell, Elizabeth E.O.; Kaul, Patrick R.; Serrahn, Jill N.; Murhammer, David W.; Linhardt, Robert J.; Weiler, John M. (2001-01-01)
      C1 esterase inhibitor (C1INH) is an important regulator of the classical complement pathway. Hereditary deficiency of C1INH causes angioedema of the skin, gut, and respiratory tissues that may be fatal. C1INH replacement ...

    • Heparin Binding and Augmentation of C1 Inhibitor Activity 

      Caldwell, Elizabeth E.O.; Andreasen, Alan M.; Blietz, Melinda A.; Serrahn, Jill N.; Vandernoot, Victoria; Park, Youmie; Yu, Guyong; Linhardt, Robert J.; Weiler, John M. (1999-01-15)
      Heparin and other glycosaminoglycans have profound activity in vitro on the regulation of complement activity. The studies reported here examined the mechanism whereby heparin enhances C1 esterase inhibitor (C1INH) activity ...