Now showing items 1-2 of 2

    • Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages 

      Gasimli, Leyla; Hickey, Anne Marie; Yang, Bo; Li, Guoyun; Dela Rosa, Mitche; Nairn, Alison V.; Kulik, Michael J.; Dordick, Jonathan S.; Moremen, Kelley W.; Dalton, Stephen; Linhardt, Robert J. (Elsevier, 2014-01-01)
      Background: Proteoglycans are found on the cell surface and in the extracellular matrix, and serve as prime sites for interaction with signaling molecules. Proteoglycans help regulate pathways that control stem cell fate, ...
    • Glycomics of Proteoglycan Biosynthesis in Murine Embryonic Stem Cell Differentiation 

      Nairn, Alison V.; Kinoshita-Toyoda, Akiko; Toyoda, Hidenao; Xie, Jin; Harris, Kyle; Dalton, Stephen; Kulik, Michael; Pierce, J. Michael; Toida, Toshihiko; Moremen, Kelley W.; Linhardt, Robert J. (American Chemical Society (ACS), 2007-11-01)
      Glycosaminoglycans (GAGs) play a critical role in binding and activation of growth factors involved in cell signaling critical for developmental biology. The biosynthetic pathways for GAGs have been elucidated over the ...