Now showing items 1-3 of 3

    • Accelerated Heparin Stability Studies 

      Jandik, Kenneth A.; Kruep, Dale; Cartier, Michelle; Linhardt, Robert J. (1996-01-01)
      The objective of this study was to extend our understanding of the stability of heparin. Sodium heparin, derived from porcine intestinal mucosa, was first incubated in 0.1 N hydrochloric acid and 0.1 N sodium hydroxide at ...
    • Action Pattern of Polysaccharide Lyases on Glycosaminoglycans 

      Jandik, Kenneth A.; Gu, Kenan; Linhardt, Robert J. (1994-06-01)
      The action pattern of polysaccharide lyases on glycosaminoglycan substrates was examined using viscosimetric measurements and gradient polyacrylamide gel electrophoresis (PAGE). Heparin lyase I (heparinase, EC and ...
    • Preparation and Structural Characterization of Large Heparin-Derived Oligosaccharides 

      Pervin, Azra; Gallo, Cindy; Jandik, Kenneth A.; Han, Xue Jun; Linhardt, Robert J. (1995-02-01)
      Porcine mucosal heparin was partially depolymerized with heparin lyase I and then fractionated into low-molecular-weight (< 5000) and high-molecular-weight (> 5000) oligosaccharides by pressure filtration. The high-molec ...