Browsing Linhardt Research Labs Papers by Author "Orfila, James E."

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    • Circulating heparan sulfate fragments mediate septic cognitive dysfunction 

      Hippensteel, Joseph A.; Anderson, Brian J.; Orfila, James E.; McMurtry, Sarah A.; Dietz, Robert M.; Su, Guowei; Ford, Joshay A.; Oshima, Kaori; Yang, Yimu; Zhang, Fuming; Han, Xiaorui; Yu, Yanlei; Liu, Jian; Linhardt, Robert J.; Meyer, Nuala J.; Herson, Paco S.; Schmidt, Eric P. (2019-01-01)
      Septic patients frequently develop cognitive impairment that persists beyond hospital discharge. The impact of sepsis on electrophysiological and molecular determinants of learning is underexplored. We observed that mice ...