Browsing Linhardt Research Labs Papers by Author "Palermo, Maria C."

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Determination of the Composition of the Oligosaccharide Phosphate Fraction of Pichia holstii NRRL Y-2448 Phosphomannan by Capillary Electrophoresis and HPLC

Ferro, Vito; Li, Caiping; Fewings, Kym; Palermo, Maria C.; Linhardt, Robert J.; Toida, Toshihiko (2002-01-01)

The promising new anticancer agent, PI-88, is prepared by the sulfonation of the oligosaccharide phosphate fraction of the extracellular phosphomannan produced by the yeast Pichia (Hansenula) holstii NRRL Y-2448. The ...
Preparation and anticoagulant activity of phosphosulfomannan PI-88

Yu, Guangli; Gunay, Nur Sibel; Linhardt, Robert J.; Toida, Toshihiko; Fareed, Jawed; Hoppensteadt, Debra A.; Shadid, Hazar; Ferro, Vito; Li, Caiping; Fewings, Kym; Palermo, Maria C.; Podger, Denis (2002-10-01)

A yeast-derived phosphomannan mixture was chemically sulfonated and the composition and structure of the product mixture was studied. This phosphosulfomannan mixture, PI-88, is currently under clinical evaluation as an ...