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    • Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure 

      Arnold, Katelyn; Xu, Yongmei; Sparkenbaugh, Erica M.; Li, Miaomiao; Han, Xiaorui; Zhang, Xing; Xia, Ke; Piegore, Mark; Zhang, Fuming; Zhang, Xiaoxiao; Henderson, Mike; Pagadala, Vijayakanth; Su, Guowei; Tan, Lisi; Park, Pyong Woo; Stravitz, Richard T.; Key, Nigel S.; Linhardt, Robert J.; Pawlinski, Rafal; Xu, Ding; Liu, Jian (American Association for the Advancement of Science (AAAS), 2020-03-18)
      Acetaminophen/paracetamol (APAP) overdose is the leading cause of drug-induced acute liver failure (ALF) in the United States and Europe. The progression of the disease is attributed to sterile inflammation induced by the ...