Browsing Linhardt Research Labs Papers by Author "Tanner, M.E."

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Structure/function analysis of the Pasteurella multocida heparosan synthases: towards defining enzyme specificity and engineering novel catalysts

Otto, N.J.; Masuko, S.; Mayer, A.; Tanner, M.E.; Linhardt, Robert J.; DeAngelis, P.L. (The American Society for Biochemistry and Molecular Biology (ASBMB) and Elsevier, 2012)

The Pasteurella multocida heparosan synthases, PmHS1 and PmHS2, are homologous (∼65% identical) bifunctional glycosyltransferase proteins found in Type D Pasteurella. These unique enzymes are able to generate the ...