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    • Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation 

      Hippensteel, Joseph A.; Uchimido, Ryo; Tyler, Patrick D.; Burke, Ryan C.; Han, Xiaorui; Zhang, Fuming; McMurtry, Sarah A.; Colbert, James F.; Lindsell, Christopher J.; Angus, Derek C.; Kellum, John A.; Yealy, Donald M.; Linhardt, Robert J.; Shapiro, Nathan I.; Schmidt, Eric P. (Springer Nature, 2019-07-23)
      Background: Intravenous fluids, an essential component of sepsis resuscitation, may paradoxically worsen outcomes by exacerbating endothelial injury. Preclinical models suggest that fluid resuscitation degrades the endothelial ...