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    • Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure 

      Ko, Kenta; Suzuki, Takehiro; Ishikawa, Ryota; Hattori, Natsuko; Ito, Risako; Umehara, Kenta; Furihata, Tomomi; Dohmae, Naoshi; Linhardt, Robert J.; Igarashi, Kazuei; Toida, Toshihiko; Higashi, Kyohei (The American Society for Biochemistry and Molecular Biology (ASBMB) and Elsevier, 2020-12-25)
      Infiltration of peripheral immune cells after blood-brain barrier dysfunction causes severe inflammation after a stroke. Although the endothelial glycocalyx, a network of membrane-bound glycoproteins and proteoglycans that ...