Browsing Linhardt Research Labs Papers by Author "Urbanowicz, Paulina A."

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    • Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown 

      Crouch, Lucy I.; Liberato, Marcelo V.; Urbanowicz, Paulina A.; Baslé, Arnaud; Lamb, Christopher A.; Stewart, Christopher J.; Cooke, Katie; Doona, Mary; Needham, Stephanie; Brady, Richard R.; Berrington, Janet E.; Madunic, Katarina; Wuhrer, Manfred; Chater, Peter; Pearson, Jeffery P.; Glowacki, Robert; Martens, Eric C.; Zhang, Fuming; Linhardt, Robert J.; Spencer, Daniel I.R.; Bolam, David N. (Nature, 2020-12-01)
      The thick mucus layer of the gut provides a barrier to infiltration of the underlying epithelia by both the normal microbiota and enteric pathogens. Some members of the microbiota utilise mucin glycoproteins as a nutrient ...