Browsing Linhardt Research Labs Papers by Author "Van Doren, S.R."

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    • Heparinoids activate a tumor-secreted protease via tethering and V-type allostery 

      Fulcher, Y.G.; Gari, R.R.S.; Frey, N.C.; Zhang, F.; Linhardt, Robert J.; King, G.M.; Van Doren, S.R. (American Chemical Society (ACS), 2014)
      The chemoenzymatic synthesis of heparan sulfate tetrasaccharide (1) and hexasaccharide (2) with a fluorous tag attached at the reducing end is reported. The fluorous tert-butyl dicarbonate (FBoc) tag did not interfere with ...