Browsing Linhardt Research Labs Papers by Author "Van Doren, Steven R."

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    • Glycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7 

      Fulcher, Yan G.; Prior, Stephen H.; Masuko, Sayaka; Li, Lingyun; Pu, Dennis; Zhang, Fuming; Linhardt, Robert J.; Van Doren, Steven R. (2017-07-05)
      Heparan sulfate proteoglycans activate the matrix metalloproteinase-7 zymogen (proMMP-7) and recruit it in order to shed proteins from cell surfaces. This occurs in uterine and mammary epithelia, bacterial killing, lung ...