Browsing Linhardt Research Labs Papers by Author "Van Kuppevelt, Toin H."

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    • Cellular Binding of Hepatitis C Virus Envelope Glycoprotein E2 Requires Cell Surface Heparan Sulfate 

      Barth, Heidi; Schäfer, Christiane; Adah, Mohammed I.; Zhang, Fuming; Linhardt, Robert J.; Toyoda, Hidenao; Kinoshita-Toyoda, Akiko; Toida, Toshihiko; Van Kuppevelt, Toin H.; Depla, Erik; Von Weizsäcker, Fritz; Blum, Hubert E.; Baumert, Thomas F. (Elsevier, 2003-10-17)
      The conservation of positively charged residues in the N terminus of the hepatitis C virus (HCV) envelope glycoprotein E2 suggests an interaction of the viral envelope with cell surface glycosaminoglycans. Using recombinant ...

    • Human Single Chain Antibodies Against Heparin: Selection, Characterization and Effect on Coagulation 

      Van de Westerlo, Els M.A.; Smetsers, Toon F.C.M.; Dennissen, Michel A.B.A.; Linhardt, Robert J.; Veerkamp, Jacques H.; Van Muijen, Goos N.P.; Van Kuppevelt, Toin H. (2002-04-01)
      Heparin, located in mast cells and basophilic granulocytes, is widely used as an anticoagulant. It belongs to a class of linear polysaccharides called glycosaminoglycans (GAGs). Using phage display technology, we have ...