Browsing Linhardt Research Labs Papers by Author "Wang, Hong"
Now showing items 1-5 of 5
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Chemobiocatalytic Synthesis of a Low Molecular Weight Heparin
Yu, Yanlei; Fu, Li; He, Peng; Xia, Ke; Varghese, Sony; Wang, Hong; Zhang, Fuming; Dordick, Jonathan; Linhardt, Robert J. (2022-03-18)Heparin products are widely used clinical anticoagulants essential in the practice of modern medicine. Low-molecular-weight heparins (LMWHs) are currently prepared by the controlled chemical or enzymatic depolymerization ... -
Inhibition of glucuronomannan hexamer on the proliferation of lung cancer through binding with immunoglobulin G
Jin, Weihua; He, Xinyue; Zhu, Jiachen; Fang, Qiufu; Wei, Bin; Sun, Jiadong; Zhang, Wenjing; Zhang, Zhongshan; Zhang, Fuming; Linhardt, Robert J.; Wang, Hong; Zhong, Weihong (2020-11-15)The anti-lung cancer activity of oligosaccharides derived from glucuronomannan was investigated. The inhibition of A549 cell proliferation by glucuronomannan (Gn) and its oligomers (dimer (G2), tetramer (G4) and hexamer ... -
Structural analysis of a novel sulfated galacto-fuco-xylo-glucurono-mannan from Sargassum fusiforme and its anti-lung cancer activity
Jin, Weihua; Tang, Hong; Zhang, Jinmei; Wei, Bin; Sun, Jiadong; Zhang, Wenjing; Zhang, Fuming; Wang, Hong; Linhardt, Robert J.; Zhong, Weihong (2020-04-15)Polysaccharide (HFSGF) was purified from Sargassum fusiforme. Autohydrolysis and gel column chromatography were performed to fractionate HFSGF into three components (HFSGF-S, HFSGF-L and HFSGF-H). Compositional analysis, ... -
Structural characteristics and anti-complement activities of polysaccharides from Sargassum hemiphyllum
Jin, Weihua; Fang, Qiufu; Jiang, Di; Li, Tongtong; Wei, Bin; Sun, Jiadong; Zhang, Wenjing; Zhang, Zhongshan; Zhang, Fuming; Linhardt, Robert J.; Wang, Hong; Zhong, Weihong (2020-10-01)Three polysaccharides (SH-1, SH-2 and SH-3) were purified from a brown macroalgea, Sargassum hemiphyllum. The autohydrolysis products from each polysaccharide were separated to three fractions (S fractions as oligomers, L ... -
Structural characterization and anti-lung cancer activity of a sulfated glucurono-xylo-rhamnan from Enteromorpha prolifera
Jin, Weihua; He, Xinyue; Long, Liufei; Fang, Qiufu; Wei, Bin; Sun, Jiadong; Zhang, Wenjing; Wang, Hong; Zhang, Fuming; Linhardt, Robert J. (2020-06-01)A sulfated glucurono-xylo-rhamnan (EP-3-H) was purified from a green alga, Enteromorpha prolifera. EP-3-H and its oligomers were characterized by high performance liquid chromatography, mass spectrometry and one and ...