Browsing Linhardt Research Labs Papers by Author "Wang, Hui M."
Now showing items 1-4 of 4
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Analysis of Glycosaminoglycan-Derived Oligosaccharides Using Fast Atom Bombardment Mass Spectrometry
Linhardt, Robert J.; Wang, Hui M.; Loganathan, Duraikkannu; Lamb, Diane J.; Mallis, Larry M. (1992-02-17)Glycosaminoglycans (GAGS) are sulfated, linear polysaccharides found in mammalian tissues’, that play an important role in cell-cell interaction2 and demonstrate a wide variety of other important biological activities3. ... -
Negative-Ion Fast Atom Bombardment Tandem Mass Spectrometry to Determine Sulfate and Linkage Position in Glycosaminoglycan-Derived Disaccharides
Lamb, Diane J.; Wang, Hui M.; Mallis, Larry M.; Linhardt, Robert J. (1992-01-01)Negative ion fast-atom bombardment tandem mass spectrometry has been used in the analysis of monosulfated. disaccharides. These commercially obtained disaccharides have been enzymatically prepared from glycosaminoglycans ... -
Sequence Analysis of Highly Sulfated Heparin-Derived Oligosaccharides Using Fast Atom Bombardment Mass Spectrometry
Mallis, Larry M.; Wang, Hui M.; Loganathan, Duraikkannu; Linhardt, Robert J. (1989-01-01)Heparin, a polydisperse, sulfated copolymer of 1----4 linked glucosamine and uronic acid residues, has been used clinically as an anticoagulant for half a century. Despite a yearly use of over 50 million doses in the U.S. ... -
Structural Variation of the Antithrombin III Binding Site and its Occurrence in Heparin from Different Sources
Loganathan, Duraikkannu; Wang, Hui M.; Mallis, Larry M.; Linhardt, Robert J. (1990-05-01)A tetrasaccharide possessing a biosynthetically permissible structural variability in and adjacent to the antithrombin III (ATIII) binding site has been isolated from heparin lyase depolymerized bovine lung heparin by using ...