Browsing Linhardt Research Labs Papers by Author "Xia, Kai"

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Characterization and comparative analysis of toxin–antitoxin systems in Acetobacter pasteurianus

Xia, Kai; Bao, Han; Zhang, Fuming; Linhardt, Robert J.; Liang, Xinle (2019-06-01)

Bacterial toxin-antitoxin (TA) systems play important roles in diverse cellular regulatory processes. Here, we characterize three putative type II TA candidates from Acetobacter pasteurianus and investigate the profile of ...
Copper regulates the interactions of antimicrobial piscidin peptides from fish mast cells with formyl peptide receptors and heparin

Kim, So Young; Zhang, Fuming; Gong, Wanghua; Chen, Keqiang; Xia, Kai; Liu, Fei; Gross, Richard; Wang, Ji Ming; Linhardt, Robert J.; Cotten, Myriam L. (Elsevier, 2018-10-05)

Phagocytic cells in fish secrete antimicrobial peptides (AMPs) such as piscidins, glycosaminoglycans such as heparin, and copper ions as first-line immune defenses. Recently, we established that Cu2+ coordination by piscidins ...