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dc.contributor.authorCai, Chao
dc.contributor.authorEdgar, Kristi
dc.contributor.authorLiu, Jian
dc.contributor.authorLinhardt, Robert J.
dc.date2013
dc.date.accessioned2022-06-23T03:26:40Z
dc.date.available2022-06-23T03:26:40Z
dc.date.issued2013-05-03
dc.identifier.citationPreparation and application of a “clickable acceptor for enzymatic synthesis of heparin oligosaccharides," C. Cai, K. Edgar, J. Liu, R.J. Linhardt, Carbohydrate Research, 372, 30–34, 2013.
dc.identifier.issn1873426X
dc.identifier.issn86215
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5145
dc.identifier.urihttps://doi.org/10.1016/j.carres.2013.02.010
dc.descriptionCarbohydrate Research, 372, 30–34
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractA 'clickable' disaccharide was prepared by treating the aldehyde precursor with hydroxylamine, followed by the catalytic hydrogenation and diazotransfer reaction. This disaccharide was successfully applied to the elongation of the backbone construction of ultralow molecular weight (ULMW) heparins using two bacterial glycosyl transferases, N-acetyl glucosaminyl transferase from Escherichia coli K5 (KfiA) and heparosan synthase-2 (pmHS2) from Pasteurella multocida.
dc.description.sponsorshipNational Institutes of Health
dc.languageen_US
dc.language.isoENG
dc.publisherElsevier
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofCarbohydrate Research
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titlePreparation and application of a “clickable” acceptor for enzymatic synthesis of heparin oligosaccharides
dc.typeArticle
dcterms.accessRightsA full text version is available in DSpace@RPI
dcterms.isPartOfJournal
dcterms.isVersionOfhttps://doi.org/10.1016/j.carres.2013.02.010
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.pages30-34
rpi.description.volume372


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