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dc.contributor.authorLinhardt, Robert J.
dc.contributor.authorAvci, Fikri Y.
dc.contributor.authorToida, Toshihiko
dc.contributor.authorKim, Yeong Shik
dc.contributor.authorCygler, Miroslaw
dc.date2006
dc.date.accessioned2022-06-23T03:26:41Z
dc.date.available2022-06-23T03:26:41Z
dc.date.issued2006-12-01
dc.identifier.citationCS Lyases: Structure, Activity and Applications in Analysis and the Treatment of Diseases, R.J. Linhardt, F.Y. Avci, T. Toida, Y.S. Kim, M. Cygler, Chondroitin Sulfate Structure, Role and Pharmacological Activity-Advances in Pharmacology, N. Volpi Ed., Elsevier, Chapter 9, 2006.
dc.identifier.issn10543589
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5148
dc.identifier.urihttps://doi.org/10.1016/S1054-3589(05)53009-6
dc.descriptionChondroitin Sulfate Structure, Role and Pharmacological Activity-Advances in Pharmacology, N. Volpi Ed., Elsevier, Chapter 9
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractGlycosaminoglycans (GAGs) are a family of highly sulfated, complex mixture of linear polysaccharides that display a wide array of biological activities (Boneu, 1996; Jackson et al., 1991). GAGs can be classified into four basic types—hyaluronan, chondroitin/dermatan sulfates (CS/DS), heparin/heparan sulfate, and keratan sulfate (Capila and Linhardt, 2002; Esko and Selleck, 2002; Iozzo, 1998; Linhardt and Toida, 2004). Chondroitin/dermatan sulfates are the focus of this chapter. Chondroitin/dermatan sulfates are linear, polydisperse GAGs with a repeating core of disaccharide structure composed of a d-glucopyranosyl uronic (GlcAp) acid or L-idopyranosyl uronic (IdoAp) acid glycosidically linked to 2-deoxy, 2-acetamido-d-galactopyranose (GalpNAc) residue (Fig. 1). The major classes of the chondroitin family of GAGs are: chondroitin; chondroitin-4-sulfate (CS-A); dermatan sulfate (CS-B or DS), and chondroitin-6-sulfate (CS-C).
dc.description.sponsorshipNational Heart, Lung, and Blood Institute
dc.languageen_US
dc.language.isoENG
dc.publisherElsevier
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofAdvances in Pharmacology
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleCS Lyases: Structure, Activity and Applications in Analysis and the Treatment of Diseases
dc.typeBook chapter
dcterms.accessRightsA full text version is available in DSpace@RPI
dcterms.isPartOfBook Series
dcterms.isVersionOfhttps://doi.org/10.1016/S1054-3589(05)53009-6
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.pages187-215
rpi.description.volume53


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