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    Mass Spectrometry for the Analysis of Highly Charged Sulfated Carbohydrates

    Author
    Chi, L.; Amster, J.; Linhardt, Robert J.
    ORCID
    https://orcid.org/0000-0003-2219-5833
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    MASS SPECTROMETRY FOR THE ANALYSIS OF HIGHLY CHARGED SULFATED.pdf (2.096Mb)
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    Date Issued
    2005
    Subject
    Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
    Degree
    Terms of Use
    In Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/;
    Full Citation
    Mass Spectrometry for the Analysis of Highly Charged Sulfated Carbohydrates, L. Chi, J. Amster, R.J. Linhardt, Current Analytical Chemistry,1, 223-240, 2005.
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    URI
    https://hdl.handle.net/20.500.13015/5152; https://doi.org/10.2174/157341105774573929
    Abstract
    Sulfated polysaccharides and their oligosaccharide components play an important biological role in physiological and pathophysiological processes. Glycosaminoglycans, such as heparin, are currently used as pharmaceutical agents to control coagulation. Moreover, there arc intensive efforts in developing rapid approaches for the analysis of such bioactive carbohydrates to assess their pharmacological activity and in glycomic applications. Soft ionization methods of mass spectrometry have been applied with recent success in the analysis of sulfated carbohydrates. This review will examine the application of mass spectrometry in the compositional analysis and structural characterization of these important highly charged molecules.;
    Description
    Current Analytical Chemistry,1, 223-240; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
    Department
    The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
    Publisher
    Bentham Science
    Relationships
    The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; https://harc.rpi.edu/;
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    A full text version is available in DSpace@RPI;
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