Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
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Solid-Phase Chemoenzymatic Synthesis of Neuraminic Acid Based C-glycosides, S.N. Baytas, Q. Wang, N.A. Karst, R.J. Linhardt, Journal of Organic Chemistry, 69, 6900-6903, 2004.
The chemoenzymatic regioselective acylation of Neu5Ac followed by SmI2-mediated C-glycosylation on a solid support is described for five C-glycosides. This method should facilitate the construction of combinatorial libraries of inhibitors of neuraminidase activity and hemagglutinin interaction as potential antiviral agents.;
Journal of Organic Chemistry, 69, 6900-6903; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
American Chemical Society (ACS)
The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; https://harc.rpi.edu/;