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    Solid-Phase Chemoenzymatic Synthesis of Neuraminic Acid Based C-glycosides

    Author
    Baytas, S.N.; Wang, Qun; Karst, N.A.; Linhardt, Robert J.
    ORCID
    https://orcid.org/0000-0003-2219-5833
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    SOLID-PHASE CHEMOENZYMATIC SYNTHESIS OF C-SIALOSIDES.pdf (913.3Kb)
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    Date Issued
    2004
    Subject
    Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
    Degree
    Terms of Use
    In Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/;
    Full Citation
    Solid-Phase Chemoenzymatic Synthesis of Neuraminic Acid Based C-glycosides, S.N. Baytas, Q. Wang, N.A. Karst, R.J. Linhardt, Journal of Organic Chemistry, 69, 6900-6903, 2004.
    Metadata
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    URI
    https://hdl.handle.net/20.500.13015/5156; https://doi.org/10.1021%2Fjo0491298
    Abstract
    The chemoenzymatic regioselective acylation of Neu5Ac followed by SmI2-mediated C-glycosylation on a solid support is described for five C-glycosides. This method should facilitate the construction of combinatorial libraries of inhibitors of neuraminidase activity and hemagglutinin interaction as potential antiviral agents.;
    Description
    Journal of Organic Chemistry, 69, 6900-6903; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
    Department
    The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
    Publisher
    American Chemical Society (ACS)
    Relationships
    The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; https://harc.rpi.edu/;
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    A full text version is available in DSpace@RPI;
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