| dc.contributor.author | Du, Y. | |
| dc.contributor.author | Liu, J, | |
| dc.contributor.author | Linhardt, Robert J. | |
| dc.date | 2006 | |
| dc.date.accessioned | 2022-06-23T03:56:10Z | |
| dc.date.available | 2022-06-23T03:56:10Z | |
| dc.date.issued | 2006 | |
| dc.identifier.citation | Stereoselective Synthesis of Cytotoxic Anhydrophytosphingosine Pachastrissamine (Jaspine B) from D-Xylose, Y. Du, J, Liu, R.J. Linhardt, Journal of Organic Chemistry, 71, 1251-1253, 2006. | |
| dc.identifier.uri | https://hdl.handle.net/20.500.13015/5182 | |
| dc.identifier.uri | https://doi.org/10.1021/jo051644y | |
| dc.description | Journal of Organic Chemistry, 71, 1251-1253 | |
| dc.description | Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform. | |
| dc.description.abstract | The first naturally occurring anhydrophytosphingosine, pachastrissamine (jaspine B), a marine compound cytotoxic toward P388, A549, HT29, and MEL28 cell lines at IC(50) = 0.01 microg/mL level, has been stereoselectively synthesized from D-xylose in 10 linear steps with 25.7% overall yield. | |
| dc.language | en_US | |
| dc.language.iso | ENG | |
| dc.publisher | American Chemical Society (ACS) | |
| dc.relation.ispartof | The Linhardt Research Labs Online Collection | |
| dc.relation.ispartof | Rensselaer Polytechnic Institute, Troy, NY | |
| dc.relation.uri | https://harc.rpi.edu/ | |
| dc.subject | Biology | |
| dc.subject | Chemistry and chemical biology | |
| dc.subject | Chemical and biological engineering | |
| dc.subject | Biomedical engineering | |
| dc.title | Stereoselective Synthesis of Cytotoxic Anhydrophytosphingosine Pachastrissamine (Jaspine B) from D-Xylose | |
| dc.type | Article | |
| dcterms.accessRights | A full text version is available in DSpace@RPI | |
| dcterms.isVersionOf | https://doi.org/10.1021/jo051644y | |
| dc.rights.holder | In Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/ | |
| dc.creator.identifier | https://orcid.org/0000-0003-2219-5833 | |
| dc.relation.department | The Linhardt Research Labs. | |
| dc.relation.department | The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS) | |
