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    Combinatorial Enzymatic Synthesis of Heparan Sulfate

    Author
    Linhardt, Robert J.; Kim, Jin Hwan
    ORCID
    https://orcid.org/0000-0003-2219-5833
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    COMBINATORIAL ENZYMATIC SYNTHESIS OF HEPARAN SULFATE.pdf (282.9Kb)
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    Date Issued
    2007-09-21
    Subject
    Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
    Degree
    Terms of Use
    In Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/;
    Full Citation
    Combinatorial Enzymatic Synthesis of Heparan Sulfate, J.-H. Kim, R. J. Linhardt, Chemistry & Biology, 14, 972-973, 2007.
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    URI
    https://hdl.handle.net/20.500.13015/5199; https://doi.org/10.1016/j.chembiol.2007.09.002
    Abstract
    Escherichia coli K5 heparosan was enzymatically modified by Chen and colleagues to construct a library of heparan sulfate polysaccharides for evaluation, leading to the discovery that a 2-O-sulfoiduronic acid residue is not essential for antithrombin-mediated anticoagulant activity in larger oligosaccharide and polysaccharide structures.;
    Description
    Chemistry & Biology, 14, 972-973; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
    Department
    The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
    Publisher
    Elsevier
    Relationships
    The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; Chemistry and Biology; https://harc.rpi.edu/;
    Access
    Open Access; Elsevier User License https://www.elsevier.com/about/policies/open-access-licenses/elsevier-user-license; A full text version is available in DSpace@RPI;
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