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dc.contributor.authorLi, Boyangzi
dc.contributor.authorLiu, Haiying
dc.contributor.authorZhang, Zhenqing
dc.contributor.authorStansfield, Hope E.
dc.contributor.authorDordick, Jonathan S.
dc.contributor.authorLinhardt, Robert J.
dc.date2011
dc.date.accessioned2022-06-23T04:08:41Z
dc.date.available2022-06-23T04:08:41Z
dc.date.issued2011-12-01
dc.identifier.citationAnalysis of glycosaminoglycans in stem cell glycomics, B. Li, H. Liu, Z. Zhang, H. Stansfield, J.S. Dordick, R.J. Linhardt, in Embryonic Stem Cell Therapy for Osteodegenerative Diseases. Nicole zur Nieden, Ed., Humana Press, Methods in Molecular Biology 690, 285-300, 2011.
dc.identifier.issn10643745
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5244
dc.identifier.urihttps://doi.org/10.1007/978-1-60761-962-8_19
dc.descriptionin Embryonic Stem Cell Therapy for Osteodegenerative Diseases. Nicole zur Nieden, Ed., Humana Press, Methods in Molecular Biology 690, 285-300
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractGlycosaminoglycans (GAGs) play a critical role in the binding and activation of growth factors in cell signal transduction required for biological development. A glycomics approach can be used to examine GAG content, composition, and structure in stem cells in order to characterize their general differentiation. Specifically, this method may be used to evaluate chondrogenic differentiations by profiling for the GAG content of the differentiated cells. Here, embryonic-like teratocarcinoma cells, NCCIT, a developmentally pluripotent cell line, were used as a model for establishing GAG glycomic methods, but will be easily transferrable to embryonic stem cell cultures.
dc.description.sponsorshipNational Institute of General Medical Sciences
dc.languageen_US
dc.language.isoENG
dc.publisherSpringer
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofMethods in Molecular Biology
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleAnalysis of glycosaminoglycans in stem cell glycomics
dc.typeArticle
dcterms.accessRightsA full text version is available in DSpace@RPI
dcterms.isPartOfBook Series
dcterms.isVersionOfhttps://doi.org/10.1007/978-1-60761-962-8_19
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.pages285-300
rpi.description.volume690


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