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dc.contributor.authorLaremore, Tatiana N.
dc.contributor.authorLeach, Franklin E.
dc.contributor.authorSolakyildirim, Kemal
dc.contributor.authorAmster, I. Jonathan
dc.contributor.authorLinhardt, Robert J.
dc.date2010
dc.date.accessioned2022-06-23T04:08:42Z
dc.date.available2022-06-23T04:08:42Z
dc.date.issued2010-01-01
dc.identifier.citationGlycosaminoglycan characterization by electrospray ionization mass spectrometry including Fourier transform mass spectrometry, T. N. Laremore, F. E. Leach III, K. Solakyildirim, I. J. Amster, R. J. Linhardt, Methods in Enzymology, 478, 79-108, 2010.
dc.identifier.issn766879
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5249
dc.identifier.urihttps://doi.org/10.1016/S0076-6879(10)78003-4
dc.descriptionMethods in Enzymology, 478, 79-108
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractElectrospray ionization mass spectrometry (ESI MS) is a versatile analytical technique in glycomics of glycosaminoglycans (GAGs). Combined with enzymology, ESI MS is used for assessing changes in disaccharide composition of GAGs biosynthesized under different environmental or physiological conditions. ESI coupled with high-resolution mass analyzers such as a Fourier transform mass spectrometer (FTMS) permits accurate mass measurement of large oligosaccharides and intact GAGs as well as structural characterization of GAG oligosaccharides using information-rich fragmentation methods such as electron detachment dissociation. The first part of this chapter describes methods for disaccharide compositional profiling using ESI MS and the second part is dedicated to FTMS and tandem MS methods of GAG compositional and structural analysis.
dc.description.sponsorshipNational Institutes of Health
dc.languageen_US
dc.language.isoENG
dc.publisherElsevier
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofMethods in Enzymology
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleGlycosaminoglycan characterization by electrospray ionization mass spectrometry including Fourier transform mass spectrometry
dc.typeArticle
dcterms.accessRightsA full text version is available in DSpace@RPI
dcterms.isPartOfBook Series
dcterms.isVersionOfhttps://doi.org/10.1016/S0076-6879(10)78003-4
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.pages79-108
rpi.description.volume478


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