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dc.contributor.authorYang, B.
dc.contributor.authorWeyers, A.
dc.contributor.authorBaik, J.Y.
dc.contributor.authorSterner, E.
dc.contributor.authorSharfstein, S.
dc.contributor.authorMousa, S.A.
dc.contributor.authorZhang, F.
dc.contributor.authorDordick, J.S.
dc.contributor.authorLinhardt, Robert J.
dc.date2011
dc.date.accessioned2022-06-23T04:11:28Z
dc.date.available2022-06-23T04:11:28Z
dc.date.issued2011
dc.identifier.citationUltraperformance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis, B. Yang, A. Weyers, J. Y. Baik, E. Sterner, S. Sharfstein, S. A. Mousa, F. Zhang, J. S. Dordick, R. J. Linhardt, Analytical Biochemistry, 415, 59–66, 2011.
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5288
dc.identifier.urihttps://doi.org/10.1016/j.ab.2011.04.003
dc.descriptionAnalytical Biochemistry, 415, 59–66
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractA high resolution method for the separation and analysis of disaccharides prepared from heparin and heparan sulfate (HS) using heparin lyases is described. Ultraperformance liquid chromatography in a reverse-phase, ion-pairing mode efficiently separates eight heparin/HS disaccharides. The disaccharides can then be detected and quantified using electrospray ionization mass spectrometry. This method is particularly useful in the analysis of small amounts of biological samples, including cells, tissues and biological fluids, as it provides high sensitivity without being subject to interference from proteins, peptides and other sample impurities.
dc.languageen_US
dc.language.isoENG
dc.publisherElsevier
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleUltraperformance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis
dc.typeArticle
dcterms.accessRightsA full text version is available in DSpace@RPI
dcterms.isVersionOfhttps://doi.org/10.1016/j.ab.2011.04.003
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)


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