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dc.contributor.authorBhattacharya, Somdatta
dc.contributor.authorKim, Domyoung
dc.contributor.authorGopal, Sneha
dc.contributor.authorTice, Aaron
dc.contributor.authorLang, Kening
dc.contributor.authorDordick, Jonathan S.
dc.contributor.authorPlawsky, Joel L., 1957-
dc.contributor.authorLinhardt, Robert J.
dc.date2020
dc.date.accessioned2022-06-23T04:45:57Z
dc.date.available2022-06-23T04:45:57Z
dc.date.issued2020-11-01
dc.identifier.citationAntimicrobial effects of positively charged, conductive electrospun polymer fibers, S. Bhattacharya, D. Kim, S. Gopal, A. Tice, K. Lang, J. S. Dordick, J. L. Plawsky, R. J. Linhardt, Materials Science & Engineering C, 116 ,111247, 2020.
dc.identifier.issn18730191
dc.identifier.issn9284931
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5391
dc.identifier.urihttps://doi.org/10.1016/j.msec.2020.111247
dc.descriptionMaterials Science & Engineering C, 116 ,111247
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractIn recent years, electrospun polymer fibers have gained attention for various antibacterial applications. In this work, the effect of positively charged polymer fiber mats as antibacterial gauze is studied using electrospun poly(caprolactone) and polyaniline nanofibers. Chloroxylenol, an established anti-microbial agent is used for the first time as a secondary dopant to polyaniline during the electrospinning process to make the surface of the polyaniline fiber positively charged. Both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli are used to investigate the antibacterial activity of the positively charged and uncharged polymer surfaces. The results surprisingly show that the polyaniline surface can inhibit the growth of both bacteria even when chloroxylenol is used below its minimum inhibitory concentration. This study provides new insights allowing the better understanding of dopant-based, intrinsically conducting polymer surfaces for use as antibacterial fiber mats.
dc.description.sponsorshipNational Institutes of Health
dc.languageen_US
dc.language.isoENG
dc.publisherElsevier
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofMaterials Science and Engineering C
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleAntimicrobial effects of positively charged, conductive electrospun polymer fibers
dc.typeArticle
dcterms.accessRightsA full text version is available in DSpace@RPI
dcterms.isPartOfJournal
dcterms.isVersionOfhttps://doi.org/10.1016/j.msec.2020.111247
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.volume116


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