Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
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Challenges of pectic polysaccharides as a prebiotic from the perspective of fermentation characteristics and anti-colitis activity, Y. Chengxiao, W. Dongmei, Z. Kai, L. Hou, H. Xiao, T. Ding, D. Liu, X. Ye, R. J. Linhardt, S. Chen, Carbohydrate Polymers, 270, 118377, 2021.
Several studies are described that contribute to the systematic exploration of new aspects of digestion, fermentation, and biological activities of pectic polysaccharides (PPS) leading to a better understanding of prebiotics. Inflammatory bowel disease (IBD) is thought to be associated with the dysbacteriosis induced by different environmental agents in genetically susceptible persons. PPS are considered as an indispensable gut-microbiota-accessible carbohydrate that play a dominant role in maintaining gut microbiota balance and show a better effect in ameliorating IBD than some traditional prebiotics. The aim of this review is to summarize the fermentation characteristics of PPS, highlight its role in improving IBD, and propose a view that PPS may be a new and effective prebiotic.;
Carbohydrate Polymers, 270, 118377; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; Carbohydrate Polymers; https://harc.rpi.edu/;