Show simple item record

dc.contributor.authorPan, Lin
dc.contributor.authorCai, Chao
dc.contributor.authorLiu, Chanjuan
dc.contributor.authorLiu, Di
dc.contributor.authorLi, Guoyun
dc.contributor.authorLinhardt, Robert J.
dc.contributor.authorYu, Guangli
dc.date2021
dc.date.accessioned2022-06-27T15:36:58Z
dc.date.available2022-06-27T15:36:58Z
dc.date.issued2021-06-01
dc.identifier.citationRecent Progress and Advanced Technology in Carbohydrate-Based Drug Development, L. Pan, C. Cai, C. Liu, D. Liu, G. Li, R. J. Linhardt, G. Yu, Current Opinions in Biotechnology, 69, 191–198, 2021.
dc.identifier.issn18790429
dc.identifier.issn9581669
dc.identifier.urihttps://doi.org/10.1016/j.copbio.2020.12.023
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5464
dc.descriptionCurrent Opinions in Biotechnology, 69, 191–198
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractCarbohydrates, one of the most abundant and widespread biomolecules in nature, play indispensable roles in diverse biological functions, and represent a treasure trove of untapped potential for pharmaceutical applications. Here, we provide a brief overview of carbohydrate-based drug development (CBDD) over the past two decades. More importantly, advanced techniques and methodologies related to CBDD are emerging, including enzymatic synthesis, metabolic engineering, site-specific glycoconjugation, carbohydrate libraries and microarrays as well as carbohydrate-gut microbiome evaluation. These technologies have dramatically accelerated the speed of CBDD. The recently approved drugs and emerging techniques summarized herein will inspire new sights into potential opportunities to discover novel carbohydrate drugs.
dc.description.sponsorshipNational Natural Science Foundation of China
dc.description.urihttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/j.copbio.2020.12.023
dc.languageen_US
dc.language.isoENG
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofCurrent Opinion in Biotechnology
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleRecent Progress and Advanced Technology in Carbohydrate-Based Drug Development
dc.typeArticle
dcterms.accessRightshttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/j.copbio.2020.12.023
dcterms.isPartOfJournal
dcterms.isVersionOfhttps://doi.org/10.1016/j.copbio.2020.12.023
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.pages191-198
rpi.description.volume69


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record