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    Mulberry: A review of bioactive compounds and advanced processing technology

    Author
    Wen, Peng; Hu, Teng Gen; Linhardt, Robert J.; Liao, Sen Tai; Wu, Hong; Zou, Yu Xiao
    ORCID
    https://orcid.org/0000-0003-2219-5833
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    Other Contributors
    Date Issued
    2019-01-01
    Subject
    Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
    Degree
    Terms of Use
    In Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/;
    Full Citation
    Mulberry: A review of bioactive compounds and advanced processing technology, Y. Zou, S.-T. Liao, P. Wen, R. J. Linhardt, Hong Wu, Teng-gen Hu, Trends in Food Science & Technology, 83, 138–158, 2019.
    Metadata
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    URI
    https://doi.org/10.1016/j.tifs.2018.11.017; https://hdl.handle.net/20.500.13015/5571
    Abstract
    Background: Historically, mulberry has been effectively used as a traditional medicine in Asia for the treatment of various infectious and internal diseases. It is a rich source of bioactive compounds that can promote human health. However, to date, it has not been officially or scientifically recognized because of a lack of accepted and standardized methodology for its evaluation. Numerous studies have been conducted by applying modern biotechnological tools to explore the relationship between the active ingredients in mulberry and their biological activities to solve ambiguities in their mechanism of action, opening a new horizon in traditional Chinese medicine with the potential for modernization in the near future. Scope and approach: This paper presents a concise overview on mulberry by examining its major bioactive components, including anthocyanins, polysaccharides, phenols, alkaloids and flavonoids. Recent technical advances are discussed for extraction (solid-liquid extraction, pressurized liquid extraction, supercritical-fluid extraction, microwave-assisted extraction, ultrasonic assisted extraction, enzymatic assisted extraction, solid-phase extraction) and separation (macroporous resins adsorption, silica gel chromatography, ion exchange chromatography, gel filtration chromatography, preparative liquid chromatography, countercurrent chromatography). Key findings and conclusions: The mystery behind mulberry lies in various bioactivities that have been explored by modern technologies. Studies employing efficient, systematic, and practical protocols for sample preparation and isolation integrated with various analytical systems have been applied to discover, separate, and identify analytes in natural plants especially traditional Chinese medicines and to explore the scientific principles that will benefit the standardization and modernization of natural product research.;
    Description
    Trends in Food Science & Technology, 83, 138–158; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
    Department
    The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
    Relationships
    The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; Trends in Food Science and Technology; https://harc.rpi.edu/;
    Access
    https://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/j.tifs.2018.11.017;
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