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dc.contributor.authorOkamoto, Yusuke
dc.contributor.authorHigashi, Kyohei
dc.contributor.authorLinhardt, Robert J.
dc.contributor.authorToida, Toshihiko
dc.date2018
dc.date.accessioned2022-06-27T15:51:58Z
dc.date.available2022-06-27T15:51:58Z
dc.date.issued2018-03-15
dc.identifier.citationComprehensive analysis of glycosaminoglycans from the edible shellfish, Y Okamoto, K Higashi, RJ Linhardt, T. Toida, Carbohydrate Polymers, 184, 269-276, 2018.
dc.identifier.issn1448617
dc.identifier.urihttps://doi.org/10.1016/j.carbpol.2017.12.076
dc.identifier.urihttps://hdl.handle.net/20.500.13015/5599
dc.descriptionCarbohydrate Polymers, 184, 269-276
dc.descriptionNote : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
dc.description.abstractWe have previously reported that the keratan sulfate (KS) disaccharide was branched to the C-3 position of glucuronate in chondroitin sulfate (CS)-E derived from the Mactra chinensis. We carried out the comprehensive disaccharide analysis of GAGs from 10 shellfish, Ruditapes philippinarum, Scapharca broughtonii, Mizuhopecten yessoensis, Turbo cornutus, Crassostrea nippona, Corbicula japonica, Mytilus galloprovincialis, Neptunea intersculpta, Pseudocardium sachalinense and Crassostrea gigas, to better understand the glycan structures in marine organisms. The contents of CS, heparan sulfate and hyaluronic acid and their compositions depend on the species of shellfish. Interestingly, a peak corresponding to a pentasaccharide containing KS disaccharide was observed when GAGs from T. cornutus was treated with chondroitinase (Chase) ACII but not Chase ABC. In addition, unidentified peaks were also observed when CS derived from R. philippinarum, S. broughtonii were treated with Chase ACII. These results suggest the presence of additional unidentified structure of CS in these shellfish.
dc.description.sponsorshipJapan Society for the Promotion of Science
dc.description.urihttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/j.carbpol.2017.12.076
dc.languageen_US
dc.language.isoENG
dc.relation.ispartofThe Linhardt Research Labs Online Collection
dc.relation.ispartofRensselaer Polytechnic Institute, Troy, NY
dc.relation.ispartofCarbohydrate Polymers
dc.relation.urihttps://harc.rpi.edu/
dc.subjectBiology
dc.subjectChemistry and chemical biology
dc.subjectChemical and biological engineering
dc.subjectBiomedical engineering
dc.titleComprehensive analysis of glycosaminoglycans from the edible shellfish
dc.typeArticle
dcterms.accessRightshttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1016/j.carbpol.2017.12.076
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dcterms.isVersionOfhttps://doi.org/10.1016/j.carbpol.2017.12.076
dc.rights.holderIn Copyright : this Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). https://rightsstatements.org/page/InC/1.0/
dc.creator.identifierhttps://orcid.org/0000-0003-2219-5833
dc.relation.departmentThe Linhardt Research Labs.
dc.relation.departmentThe Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS)
rpi.description.pages269-276
rpi.description.volume184


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