Author
Yang, Jianhong; Hsieh, Po Hung; Liu, Xinyue; Zhou, Wen; Zhang, Xing; Zhao, Jing; Xu, Yongmei; Zhang, Fuming; Linhardt, Robert J.; Liu, Jian
Other Contributors
Date Issued
2017-01-01
Subject
Biology; Chemistry and chemical biology; Chemical and biological engineering; Biomedical engineering
Degree
Terms of Use
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Full Citation
Construction and Characterization of Heparan Sulfate Heptasaccharide Microarray, J. Yang, P.-H.Hsieh, X. Liu, W. Zhou, X. Zhang, F. Zhang, R. J. Linhardt, J. Liu, Chemical Communications, 53, 1743-1746, 2017.
Abstract
A targeted heptasaccharide library was synthesised to prepare a heparan sulphate (HS) microarray. The array was probed with two glycan-binding proteins, HS 3-O-sulphotransferase 1 and antithrombin, demonstrating the binding selectivity between HS and proteins. The HS microarray technique will accelerate the understanding of the structure and function relationships of HS.;
Description
Chemical Communications, 53, 1743-1746; Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.
Department
The Linhardt Research Labs.; The Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS);
Relationships
The Linhardt Research Labs Online Collection; Rensselaer Polytechnic Institute, Troy, NY; Chemical Communications; https://harc.rpi.edu/;
Access
https://login.libproxy.rpi.edu/login?url=https://doi.org/10.1039/c6cc08204a;
